5-HTP

Also known as: 5-hydroxytryptophan, griffonia simplicifolia

CCautionary35/1001 studies referenced

Common dosage

50-100mg daily

Description

Direct serotonin precursor that may support mood and sleep. More targeted than L-tryptophan.

Safety & interactions

Do NOT combine with SSRIs/SNRIs — serotonin syndrome risk. Cycle use. Take with carbidopa or green tea for peripheral conversion protection.

Check all interactions →

Researched health areas

Health domains where 5-HTP has published research. Click any domain to see all supplements and habits for that area.

MMental health & wellbeing SSleep & recovery

Get notified when new research drops

Alerts when new studies affect this supplement
Add to your personal stack and track interactions
Weekly digest with evidence score changes

Premium

Upgrade to access full study-level evidence breakdowns for each outcome.

View pricing

Questions about 5-HTP

Studies on 5-HTP (1)

Health domains

Mental health & wellbeing Sleep & recovery

ProtocolEngine provides general health information based on published research. This is not medical advice. Consult a healthcare professional before starting any supplement or health protocol.