Biotin

Safety and efficacy of MD1003 (high-dose biotin) in patients with progressive multiple sclerosis (SPI2): a randomised, double-blind, placebo-controlled, phase 3 trial.

Cree Bruce A C (2020) · The Lancet. Neurology · n=326

Reversibility of the anti-FXa activity of idrabiotaparinux (biotinylated idraparinux) by intravenous avidin infusion.

Paty I (2010) · Journal of thrombosis and haemostasis : JTH · n=33

PROVIT: Supplementary Probiotic Treatment and Vitamin B7 in Depression-A Randomized Controlled Trial.

Reininghaus Eva Z (2020) · Nutrients

First-in-Human Study of the Safety, Tolerability, Pharmacokinetics and - Preliminary Dynamics of Neuroprotectant 2-Iminobiotin in Healthy Subjects.

van Hoogdalem Ewoud-Jan (2020) · Current clinical pharmacology

Efficacy of intramuscular injections of biotin and dexpanthenol in the treatment of diffuse hair loss: A randomized, double-blind controlled study comparing two brands.

Samadi Aniseh (2022) · Dermatologic therapy · n=41

Oral administration of supplementary biotin differentially influences the fertility rate and oviductal expression of avidin and avidin-related protein-2 in low- and high-fertility broiler line hens.

Daryabari H (2015) · Poultry science · n=144

Effects of biotin on growth performance and foot pad dermatitis of starter White Pekin ducklings.

Zhu Y W (2012) · British poultry science · n=576

Pregnancy and lactation alter biomarkers of biotin metabolism in women consuming a controlled diet.

Perry Cydne A (2014) · The Journal of nutrition · n=26

Effect of biotin on milk performance of dairy cattle: a meta-analysis.

Chen B (2011) · Journal of dairy science

Safety, Tolerability, and Pharmacokinetics of the Neuroprotectant 2-Iminobiotin in Patients With Large-Vessel Occlusion Ischemic Stroke Treated With Endovascular Thrombectomy.

Vos Erik M (2025) · Stroke · n=40

Supplementary biotin decreases tibial bone weight, density and strength in riboflavin-deficient starter diets for turkey poults.

Hocking P M (2013) · British poultry science

Influences of increased levels of biotin, zinc or mannan-oligosaccharides in the diet on foot pad dermatitis in growing turkeys housed on dry and wet litter.

Youssef I M I (2012) · Journal of animal physiology and animal nutrition

High-dose biotin for multiple sclerosis: A systematic review and meta-analyses of randomized controlled trials.

Espiritu Adrian I (2021) · Multiple sclerosis and related disorders · n=889

High dietary biotin levels affect the footpad and hock health of broiler chickens reared at different stocking densities and litter conditions.

Sun Z W (2017) · Journal of animal physiology and animal nutrition

Efficacy of 5% topical minoxidil versus 5 mg oral biotin versus topical minoxidil and oral biotin on hair growth in men: randomized, crossover, clinical trial.

Valentim Flávia de Oliveira (2024) · Anais brasileiros de dermatologia

MD1003 (high-dose biotin) for the treatment of progressive multiple sclerosis: A randomised, double-blind, placebo-controlled study.

Tourbah Ayman (2016) · Multiple sclerosis (Houndmills, Basingstoke, England)

Effect of feeding biotin on milk production and hoof health in lactating dairy cows: a quantitative assessment.

Lean I J (2011) · Journal of dairy science

PROVIT-CLOCK: A Potential Influence of Probiotics and Vitamin B7 Add-On Treatment and Metabolites on Clock Gene Expression in Major Depression.

Kreuzer Kathrin (2024) · Neuropsychobiology · n=53