Folate

Effect of prenatal micronutrient-fortified balanced energy-protein supplementation on maternal and newborn body composition: A sub-study from the MISAME-III randomized controlled efficacy trial in rural Burkina Faso.

Argaw Alemayehu (2023) · PLoS medicine · n=1897

The effects of folic acid supplementation on endothelial function in adults: a systematic review and dose-response meta-analysis of randomized controlled trials.

Zamani Mohammad (2023) · Nutrition journal · n=2025

Cost-effectiveness analysis of adding omega-3 or vitamin D supplementation to standard therapy in treating painful crises of pediatric sickle cell disease patients.

Abdelhalima S M (2022) · European review for medical and pharmacological sciences · n=165

Fortified Balanced Energy-Protein Supplementation, Maternal Anemia, and Gestational Weight Gain: A Randomized Controlled Efficacy Trial among Pregnant Women in Rural Burkina Faso.

Hanley-Cook Giles (2022) · The Journal of nutrition

Evaluation of multiple micronutrient supplementation and medium-quantity lipid-based nutrient supplementation in pregnancy on child development in rural Niger: A secondary analysis of a cluster randomized controlled trial.

Sudfeld Christopher R (2022) · PLoS medicine · n=53

Continuous supplementation of folic acid in pregnancy and the risk of perinatal depression-A meta-analysis.

Jin Xingyi (2022) · Journal of affective disorders · n=26275

Fortified Balanced Energy-Protein Supplements Increase Nutrient Adequacy without Displacing Food Intake in Pregnant Women in Rural Burkina Faso.

de Kok Brenda (2021) · The Journal of nutrition

Effect of Fortification with Multiple Micronutrient Powder on the Prevention and Treatment of Iron Deficiency and Anaemia in Brazilian Children: A Randomized Clinical Trial.

Machado Malaine Morais Alves (2021) · Nutrients

A community-based randomized controlled trial providing weekly iron-folic acid supplementation increased serum- ferritin, -folate and hemoglobin concentration of adolescent girls in southern Ethiopia.

Handiso Yoseph Halala (2021) · Scientific reports

Effects of maternal folic acid supplementation during the second and third trimesters of pregnancy on neurocognitive development in the child: an 11-year follow-up from a randomised controlled trial.

Caffrey Aoife (2021) · BMC medicine

Long-Chain Polyunsaturated Fatty Acids, Homocysteine at Birth and Fatty Acid Desaturase Gene Cluster Polymorphisms are Associated with Children's Processing Speed up to Age 9 Years.

Campoy Cristina (2020) · Nutrients · n=143

Effects of Maternal Fish Oil and/or 5-Methyl-Tetrahydrofolate Supplementation during Pregnancy on Offspring Brain Resting-State at 10 Years Old: A Follow-Up Study from the NUHEAL Randomized Controlled Trial.

Azaryah Hatim (2020) · Nutrients · n=33

Effect of high-dose folic acid supplementation on the prevention of preeclampsia in twin pregnancy.

Corsi Daniel J (2022) · The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · n=2464

Effect of supplementation of complex milk lipids in pregnancy on fetal growth: results from the Complex Lipids in Mothers and Babies (CLIMB) randomized controlled trial.

Norris Tom (2021) · The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

Obesity is associated with folate metabolism.

Köse Süleyman (2020) · International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition

Rate of gestational weight gain and adverse pregnancy outcomes in rural nulliparous women: a prospective cohort analysis from China.

Zhou Yubo (2019) · The British journal of nutrition

Comparing Folic Acid Dosage Strengths to Prevent Reduction in Fetal Size Among Pregnant Women Who Smoked Cigarettes: A Randomized Clinical Trial.

Yusuf Korede K (2019) · JAMA pediatrics

Effect of folate supplementation on insulin sensitivity and type 2 diabetes: a meta-analysis of randomized controlled trials.

Lind Mads Vendelbo (2019) · The American journal of clinical nutrition · n=22250

The modifying effect of the MTHFR genotype on the association between folic acid supplementation and pulse wave velocity: Findings from the CSPPT.

Yang Xin (2018) · Cardiovascular therapeutics · n=2529

Maternal Folate Intake and Risk of Childhood Brain and Spinal Cord Tumors: A Systematic Review and Meta-Analysis.

Chiavarini Manuela (2018) · Neuroepidemiology

Folic acid supplementation during the preconception period: A systematic review and meta-analysis.

Toivonen K I (2018) · Preventive medicine

The effects of folate supplementation on glucose metabolism and risk of type 2 diabetes: a systematic review and meta-analysis of randomized controlled trials.

Zhao Jie V (2018) · Annals of epidemiology

Randomized control trial comparing effectiveness of weekly versus daily antenatal oral iron supplementation in preventing anemia during pregnancy.

Goonewardene Indra Malik R (2018) · The journal of obstetrics and gynaecology research · n=106

Folic acid intake and folate status and colorectal cancer risk: A systematic review and meta-analysis.

Moazzen Sara (2018) · Clinical nutrition (Edinburgh, Scotland)

Prenatal early food and multiple micronutrient supplementation trial reduced infant mortality in Bangladesh, but did not influence morbidity.

Kallioinen Maija (2017) · Acta paediatrica (Oslo, Norway : 1992) · n=4436

Effects of folic acid fortification on orofacial clefts prevalence: a meta-analysis.

Millacura Natalia (2017) · Public health nutrition

Homocysteine and Stroke Risk: Modifying Effect of Methylenetetrahydrofolate Reductase C677T Polymorphism and Folic Acid Intervention.

Zhao Min (2017) · Stroke

Effects of a lipid-based nutrient supplement during pregnancy and lactation on maternal plasma fatty acid status and lipid profile: Results of two randomized controlled trials.

Oaks Brietta M (2017) · Prostaglandins, leukotrienes, and essential fatty acids · n=1320

Providing lipid-based nutrient supplement during pregnancy does not reduce the risk of maternal P falciparum parasitaemia and reproductive tract infections: a randomised controlled trial.

Nkhoma Minyanga (2017) · BMC pregnancy and childbirth

Effect of folic acid supplementation on preterm delivery and small for gestational age births: A systematic review and meta-analysis.

Zhang Qian (2017) · Reproductive toxicology (Elmsford, N.Y.)

Elevated homocysteine levels in mothers with neural tube defects: a systematic review and meta-analysis.

Yang Mei (2017) · The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · n=3237

Supplementation of vitamin B12 or folic acid on hemoglobin concentration in children 6-36 months of age: A randomized placebo controlled trial.

Kumar Tivendra (2017) · Clinical nutrition (Edinburgh, Scotland)

Human milk oligosaccharide composition following supplementation with folic acid vs (6S)-5-methyltetrahydrofolic acid during pregnancy and mediation by human milk folate forms.

Cochrane Kelsey M (2024) · European journal of clinical nutrition

Human milk unmetabolized folic acid is increased following supplementation with synthetic folic acid as compared to (6S)-5-methyltetrahydrofolic acid.

Cochrane Kelsey M (2023) · Scientific reports

Fortified balanced energy-protein supplementation during pregnancy and lactation and infant growth in rural Burkina Faso: A 2 × 2 factorial individually randomized controlled trial.

Argaw Alemayehu (2023) · PLoS medicine

The efficacy of irinotecan supplementation for colorectal cancer: A meta-analysis of randomized controlled studies.

Jiang Wei (2022) · Medicine

Differential Effects of Three Nutritional Supplements on the Nutrient Intake of Pregnant Women Enrolled in a Conditional Cash Transfer Program in Mexico: A Cluster Randomized Trial.

Mejía-Rodríguez Fabiola (2022) · Nutrients

Efficacy of Myo-inositol on Anthropometric, Metabolic, and Endocrine Outcomes in PCOS Patients: a Meta-analysis of Randomized Controlled Trial.

Jethaliya Hardik (2022) · Reproductive sciences (Thousand Oaks, Calif.) · n=17

Efficacy of a multivitamin adherence program based on cognitive dissonance for bariatric patients: A randomized controlled trial.

González-Sánchez Daniela Lilian (2021) · Asia Pacific journal of clinical nutrition

Folic acid supplementation and blood pressure: a GRADE-assessed systematic review and dose-response meta-analysis of 41,633 participants.

Asbaghi Omid (2023) · Critical reviews in food science and nutrition · n=41633

Effects of prenatal and postnatal maternal multiple micronutrient supplementation on child growth and morbidity in Tanzania: a double-blind, randomized-controlled trial.

Wang Dongqing (2022) · International journal of epidemiology · n=3100

Association of Infant Physical Development and Rapid Growth With Pubertal Onset Among Girls in Rural China.

Wei Jing (2021) · JAMA network open

Effects of Folic Acid Combined with DHA Supplementation on Cognitive Function and Amyloid-β-Related Biomarkers in Older Adults with Mild Cognitive Impairment by a Randomized, Double Blind, Placebo-Controlled Trial.

Bai Dong (2021) · Journal of Alzheimer's disease : JAD · n=138

Pharmacokinetics of Sodium and Calcium Salts of (6S)-5-Methyltetrahydrofolic Acid Compared to Folic Acid and Indirect Comparison of the Two Salts.

Obeid Rima (2020) · Nutrients · n=12

Prevalence and associated factors of birth defects among newborns in sub-Saharan African countries: a systematic review and meta-analysis.

Adane Fentahun (2020) · The Pan African medical journal

Impact of a nutritional supplement during gestation and early childhood on child salivary cortisol, hair cortisol, and telomere length at 4-6 years of age: a follow-up of a randomized controlled trial.

Oaks Brietta M (2020) · Stress (Amsterdam, Netherlands)

Maternal folic acid supplementation and infant birthweight in low- and middle-income countries: A systematic review.

Jonker Hannah (2020) · Maternal & child nutrition · n=9

Cytopenias among patients with rheumatic diseases using methotrexate: a meta-analysis of randomized controlled clinical trials.

Vanni Kathleen M M (2020) · Rheumatology (Oxford, England) · n=2032

Preconception and Prenatal Nutrition and Neurodevelopmental Disorders: A Systematic Review and Meta-Analysis.

Li Mengying (2019) · Nutrients

A randomized controlled trial of folic acid intervention in pregnancy highlights a putative methylation-regulated control element at ZFP57.

Irwin Rachelle E (2019) · Clinical epigenetics

Systematic Review and Bayesian Meta-analysis of the Dose-response Relationship between Folic Acid Intake and Changes in Blood Folate Concentrations.

Crider Krista S (2019) · Nutrients

Effects of dietary interventions on DNA methylation in adult humans: systematic review and meta-analysis.

ElGendy Khalil (2018) · The British journal of nutrition

[Meta-analysis on relationship between the Chinese maternal MTHFR gene polymorphism(C677T) and neural tube defects in offspring].

Zhang Chunhong (2018) · Wei sheng yan jiu = Journal of hygiene research · n=1500

A national estimate of the birth prevalence of congenital anomalies in India: systematic review and meta-analysis.

Bhide Prajkta (2018) · BMC pediatrics

Folic Acid Supplementation throughout pregnancy: psychological developmental benefits for children.

Henry Lesley-Anne (2018) · Acta paediatrica (Oslo, Norway : 1992) · n=22

Effects of folic acid supplementation on cognitive function and Aβ-related biomarkers in mild cognitive impairment: a randomized controlled trial.

Ma Fei (2019) · European journal of nutrition · n=180

Folic Acid Supplementation for Stroke Prevention in Patients With Cardiovascular Disease.

Tian Tao (2017) · The American journal of the medical sciences · n=65790

The association of folate and depression: A meta-analysis.

Bender Ansley (2017) · Journal of psychiatric research

Predictors of adherence to micronutrient supplementation before and during pregnancy in Vietnam.

Gonzalez-Casanova Ines (2017) · BMC public health

On the relationship between head circumference, brain size, prenatal long-chain PUFA/5-methyltetrahydrofolate supplementation and cognitive abilities during childhood.

Catena Andrés (2019) · The British journal of nutrition

A Village-Based Intervention: Promoting Folic Acid  Use among Rural Chinese Women.

Lin Qian (2017) · Nutrients

A pilot study of D-chiro-inositol plus folic acid in overweight patients with type 1 diabetes.

Maurizi Anna Rita (2017) · Acta diabetologica

A Meta-Analysis of the Relationship Between Maternal Folic Acid Supplementation and the Risk of Congenital Heart Defects.

Xu Aiping (2016) · International heart journal

Effects of prenatal multiple micronutrient supplementation on growth and cognition through 2 y of age in rural Bangladesh: the JiVitA-3 Trial.

Christian Parul (2016) · The American journal of clinical nutrition · n=8529

Associations between maternal stressful life events experiences and risk of neural tube defects in offspring: a systematic review and meta-analysis.

Wang Meng (2023) · The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

Congenital anomalies and risk factors in Africa: a systematic review and meta-analysis.

Moges Natnael (2023) · BMJ paediatrics open · n=983

Effectiveness of public health education on the uptake of iron and folic acid supplements among pregnant women: a stepped wedge cluster randomised trial.

Njiru Haron (2022) · BMJ open

Optimum dose of oral folic acid supplementation in transfusion-dependent thalassemia: a randomized controlled trial.

Agrawal Titiksha (2022) · Journal of tropical pediatrics

The effect of myo-inositol supplementation on the prevention of gestational diabetes in overweight pregnant women: a randomized, double-blind, controlled trial.

Esmaeilzadeh Sedighe (2023) · Minerva obstetrics and gynecology

Effects of folate supplementation on recurrence and metabolic status of cervical intraepithelial neoplasia grade 2/3 in overweight and obese women: a randomized double-blind placebo-controlled trial.

Sabihi Sima (2022) · European journal of clinical nutrition

Multivitamin Supplementation Is Associated with Greater Adequacy of Gestational Weight Gain among Pregnant Women in Tanzania.

Liu Enju (2022) · The Journal of nutrition · n=7573

Prenatal nutrition supplementation and growth biomarkers in preadolescent Bangladeshi children: A birth cohort study.

Siddiqua Towfida Jahan (2022) · Maternal & child nutrition

Magnitude and determinants of neural tube defect in Africa: a systematic review and meta-analysis.

Atlaw Daniel (2021) · BMC pregnancy and childbirth

A pilot study of thiamin and folic acid in hemodialysis patients with cognitive impairment.

Lu Renhua (2021) · Renal failure · n=3

Prenatal Folic Acid Supplements and Offspring's Autism Spectrum Disorder: A Meta-analysis and Meta-regression.

Liu Xian (2022) · Journal of autism and developmental disorders

Myo-inositol supplementation to prevent gestational diabetes in overweight non-obese women: bioelectrical impedance analysis, metabolic aspects, obstetric and neonatal outcomes - a randomized and open-label, placebo-controlled clinical trial.

Vitale Salvatore Giovanni (2021) · International journal of food sciences and nutrition

Nitrate-Rich Beetroot Juice Reduces Blood Pressure in Tanzanian Adults with Elevated Blood Pressure: A Double-Blind Randomized Controlled Feasibility Trial.

Siervo Mario (2020) · The Journal of nutrition

The impact of maternal supplementation during pregnancy and the first 6 months postpartum on the growth status of the next child born after the intervention period: Follow-up results from Bangladesh and Ghana.

Adams Katherine P (2020) · Maternal & child nutrition · n=472

Effect of continued folic acid supplementation beyond the first trimester of pregnancy on cognitive performance in the child: a follow-up study from a randomized controlled trial (FASSTT Offspring Trial).

McNulty Helene (2019) · BMC medicine

Fish oil plus wheat germ oil have no prominent effect on homocysteine levels and nutritional indices in hemodialysis patients.

Zakaria Hadeer (2021) · International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition

Effects of folic acid on oligozoospermia with MTHFR polymorphisms in term of seminal parameters, DNA fragmentation, and live birth rate: a double-blind, randomized, placebo-controlled trial.

Huang Wen-Jie (2020) · Andrology

Thymic size is increased by infancy, but not pregnancy, nutritional supplementation in rural Gambian children: a randomized clinical trial.

Moore Sophie E (2019) · BMC medicine

Does L-Methylfolate Supplement Methylphenidate Pharmacotherapy in Attention-Deficit/Hyperactivity Disorder?: Evidence of Lack of Benefit From a Double-Blind, Placebo-Controlled, Randomized Clinical Trial.

Surman Craig (2019) · Journal of clinical psychopharmacology

Effect of high dose folic acid supplementation in pregnancy on pre-eclampsia (FACT): double blind, phase III, randomised controlled, international, multicentre trial.

Wen Shi Wu (2018) · BMJ (Clinical research ed.) · n=2301

Lactating Canadian Women Consuming 1000 µg Folic Acid Daily Have High Circulating Serum Folic Acid Above a Threshold Concentration of Serum Total Folate.

Stamm Rosemary A (2018) · The Journal of nutrition · n=2

Effect of inositol stereoisomers at different dosages in gestational diabetes: an open-label, parallel, randomized controlled trial.

Fraticelli Federica (2018) · Acta diabetologica

Micronutrient supplementation during pregnancy and the risk of pregnancy-induced hypertension: A randomized clinical trial.

Chen Sen (2019) · Clinical nutrition (Edinburgh, Scotland)

Supplementation during pregnancy with small-quantity lipid-based nutrient supplements or multiple micronutrients, compared with iron and folic acid, increases women's urinary iodine concentration in semiurban Ghana: A randomized controlled trial.

Adu-Afarwuah Seth (2018) · Maternal & child nutrition

The association between maternal use of folic acid supplements during pregnancy and risk of autism spectrum disorders in children: a meta-analysis.

Wang Meiyun (2017) · Molecular autism

Maternal supplementation with small-quantity lipid-based nutrient supplements during pregnancy and lactation does not reduce depressive symptoms at 6 months postpartum in Ghanaian women: a randomized controlled trial.

Okronipa Harriet (2018) · Archives of women's mental health

Effects of Prenatal Micronutrient Supplementation on Spontaneous Preterm Birth: A Double-Blind Randomized Controlled Trial in China.

Li Zhiwen (2017) · American journal of epidemiology

The Prevention of Gestational Diabetes Mellitus With Antenatal Oral Inositol Supplementation: A Randomized Controlled Trial.

Farren Maria (2017) · Diabetes care · n=28

Folic acid supplementation increases cutaneous vasodilator sensitivity to sympathetic nerve activity in older adults.

Stanhewicz Anna E (2017) · American journal of physiology. Regulatory, integrative and comparative physiology

Stability of the human sperm DNA methylome to folic acid fortification and short-term supplementation.

Chan D (2017) · Human reproduction (Oxford, England) · n=9

Effect of folic acid supplementation during pregnancy on gestational hypertension/preeclampsia: A systematic review and meta-analysis.

Hua Xiaolin (2016) · Hypertension in pregnancy · n=2

Improving motor development in infancy with iron supplementation.

Pedley Mary (2016) · Archives of disease in childhood. Education and practice edition

Impact of Methyl-Donor Micronutrient Supplementation on DNA Methylation Patterns: A Systematic Review and Meta-Analysis of in vitro, Animal, and Human Studies.

da Mota Jhulia Caroline N L (2023) · Lifestyle genomics

The Interactions between Maternal Iron Supplementation and Iron Metabolism-Related Genetic Polymorphisms on Birth Outcomes: A Prospective Study in Chinese.

Liu Danmeng (2023) · The Journal of nutrition · n=860

The effect of folic acid supplementation on body weight and body mass index: A systematic review and meta-analysis of randomized controlled trials.

Jafari Alireza (2023) · Clinical nutrition ESPEN

Effect of nutritional supplementation on mortality in peritoneal dialysis patients: A meta-analysis.

Cui Luke (2023) · Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy

Birth prevalence of neural tube defects in eastern Africa: a systematic review and meta-analysis.

Ssentongo Paddy (2022) · BMC neurology · n=752936

Evaluation of the association between maternal folic acid supplementation and the risk of congenital heart disease: a systematic review and meta-analysis.

Cheng Zhengpei (2022) · Nutrition journal

Efficacy of 4.0 mg versus 0.4 mg Folic Acid Supplementation on the Reproductive Outcomes: A Randomized Controlled Trial.

Bortolus Renata (2021) · Nutrients · n=1060

Immunogenicity of an oral rotavirus vaccine administered with prenatal nutritional support in Niger: A cluster randomized clinical trial.

Isanaka Sheila (2021) · PLoS medicine · n=53

A Pilot Study of Silymarin as Supplementation to Reduce Toxicities in Metastatic Colorectal Cancer Patients Treated With First-Line FOLFIRI Plus Bevacizumab.

Chang Tsung-Kun (2021) · Oncology research

Myoinositol plus α-lactalbumin supplementation, insulin resistance and birth outcomes in women with gestational diabetes mellitus: a randomized, controlled study.

D'Anna Rosario (2021) · Scientific reports · n=120

Maternal Blood Pressure in Relation to Prenatal Lipid-Based Nutrient Supplementation and Adverse Birth Outcomes in a Ghanaian Cohort: A Randomized Controlled Trial and Cohort Analysis.

Abreu Alyssa M (2021) · The Journal of nutrition

Risk of malaria in young children after periconceptional iron supplementation.

Gies Sabine (2021) · Maternal & child nutrition

Effect of B vitamins supplementation on cardio-metabolic factors in patients with stable coronary artery disease: A randomized double-blind trial.

Liu Man (2020) · Asia Pacific journal of clinical nutrition

Effect of myo-inositol supplementation on ICSI outcomes among poor ovarian responder patients: A randomized controlled trial.

Nazari Leila (2020) · Journal of gynecology obstetrics and human reproduction · n=56

Cluster Randomized Trial of a Pre/Interconception Health Intervention for Mothers in Pediatric Visits.

Upadhya Krishna K (2020) · Academic pediatrics · n=415

Folic acid supplementation and risk of colorectal neoplasia during long-term follow-up of a randomized clinical trial.

Passarelli Michael N (2019) · The American journal of clinical nutrition · n=1021

Excess risk of preterm birth with periconceptional iron supplementation in a malaria endemic area: analysis of secondary data on birth outcomes in a double blind randomized controlled safety trial in Burkina Faso.

Brabin Bernard (2019) · Malaria journal · n=1959

Exposure to a Slightly Sweet Lipid-Based Nutrient Supplement During Early Life Does Not Increase the Preference for or Consumption of Sweet Foods and Beverages by 4-6-y-Old Ghanaian Preschool Children: Follow-up of a Randomized Controlled Trial.

Okronipa Harriet (2019) · The Journal of nutrition

Effect of directly observed oral iron supplementation during pregnancy on iron status in a rural population in Haryana: A randomized controlled trial.

Ahamed Farhad (2018) · Indian journal of public health

Assessment of candidate folate sensitive-differentially methylated regions in a randomised controlled trial of continued folic acid supplementation during the second and third trimesters of pregnancy.

Harrison Alan (2019) · Annals of human genetics

Prenatal and Postnatal Supplementation with Lipid-Based Nutrient Supplements Reduces Anemia and Iron Deficiency in 18-Month-Old Bangladeshi Children: A Cluster-Randomized Effectiveness Trial.

Matias Susana L (2018) · The Journal of nutrition · n=4011

Platelet Count Affects Efficacy of Folic Acid in Preventing First Stroke.

Kong Xiangyi (2018) · Journal of the American College of Cardiology

Effect of nutrient supplementation on the acquisition of humoral immunity to Plasmodium falciparum in young Malawian children.

Barua Priyanka (2018) · Malaria journal

Acceptability of multiple micronutrient powders and iron syrup in Bihar, India.

Young Melissa F (2018) · Maternal & child nutrition

Infection and Malignancy Outweigh Cardiovascular Mortality in Kidney Transplant Recipients: Post Hoc Analysis of the FAVORIT Trial.

Weinrauch Larry A (2018) · The American journal of medicine

Impact of preconceptional micronutrient supplementation on maternal mental health during pregnancy and postpartum: results from a randomized controlled trial in Vietnam.

Nguyen Phuong H (2017) · BMC women's health

The effectiveness of daily supplementation with 400 or 800 µg/day folate in reaching protective red blood folate concentrations in non-pregnant women: a randomized trial.

Obeid Rima (2018) · European journal of nutrition · n=198

[Association between maternal folate supplementation during pregnancy and the risk of autism spectrum disorder in the offspring: a Meta analysis].

Yu Xiao-Fang (2017) · Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics

Effects of an L-arginine-based multi ingredient product on endothelial function in subjects with mild to moderate hypertension and hyperhomocysteinemia - a randomized, double-blind, placebo-controlled, cross-over trial.

Reule Claudia A (2017) · BMC complementary and alternative medicine

Metformin Treatment and Homocysteine: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Zhang Qianying (2016) · Nutrients

Effect of a randomised exclusive breastfeeding counselling intervention nested into the MINIMat prenatal nutrition trial in Bangladesh.

Khan Ashraful Islam (2017) · Acta paediatrica (Oslo, Norway : 1992) · n=3188

Maternal Dietary Diversity Decreases with Household Food Insecurity in Rural Bangladesh: A Longitudinal Analysis.

Na Muzi (2016) · The Journal of nutrition · n=14600

Maternal exposure to folate antagonists and susceptibility to congenital heart disease in offspring: A systematic review and meta-analysis.

Luitel Prajjwol (2024) · British journal of clinical pharmacology

Factors associated with anemia among school-going adolescents aged 10-17 years in Zanzibar, Tanzania: a cross sectional study.

Yusufu Innocent (2023) · BMC public health

Intensified Nutrition Interventions in Antenatal Care Services Increased Consumption of Iron and Folic Acid Supplements and Early Breastfeeding Practices in Burkina Faso: Results of a Cluster-Randomized Program Evaluation.

Kim Sunny S (2023) · The Journal of nutrition · n=1920

Beneficial effects of folic acid on inflammatory markers in the patients with metabolic syndrome: Meta-analysis and meta-regression of data from 511 participants in 10 randomized controlled trials.

Jiang Zhonghui (2024) · Critical reviews in food science and nutrition · n=511

Preconception and periconception interventions to prevent low birth weight, small for gestational age and preterm birth: a systematic review and meta-analysis.

Partap Uttara (2022) · BMJ global health · n=3

Folic acid intervention during pregnancy alters DNA methylation, affecting neural target genes through two distinct mechanisms.

Ondičová Miroslava (2022) · Clinical epigenetics

Efficacy and Safety of Ferrous Bisglycinate and Folinic Acid in the Control of Iron Deficiency in Pregnant Women: A Randomized, Controlled Trial.

Bumrungpert Akkarach (2022) · Nutrients · n=120

Prenatal supplementation with multiple micronutrient supplements or medium-quantity lipid-based nutrient supplements has limited effects on child growth up to 24 months in rural Niger: a secondary analysis of a cluster randomized trial.

Bliznashka Lilia (2022) · The American journal of clinical nutrition · n=1105

Folic Acid Supplementation Improves Glycemic Control for Diabetes Prevention and Management: A Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials.

Asbaghi Omid (2021) · Nutrients

Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials.

Asbaghi Omid (2022) · Critical reviews in food science and nutrition · n=21787

The effect of Myo-inositol on fertility rates in poor ovarian responder in women undergoing assisted reproductive technique: a randomized clinical trial.

Mohammadi Sahar (2021) · Reproductive biology and endocrinology : RB&E · n=30

Preconception micronutrient supplementation positively affects child intellectual functioning at 6 y of age: A randomized controlled trial in Vietnam.

Nguyen Phuong H (2021) · The American journal of clinical nutrition

Integrating Calcium Into Antenatal Iron-Folic Acid Supplementation in Ethiopia: Women's Experiences, Perceptions of Acceptability, and Strategies to Support Calcium Supplement Adherence.

Klemm Gina C (2020) · Global health, science and practice · n=48

Feasibility and acceptability of a nutritional intervention testing the effects of nitrate-rich beetroot juice and folic acid on blood pressure in Tanzanian adults with elevated blood pressure.

Kandhari Navneet (2021) · International journal of food sciences and nutrition

The effect of folic acid throughout pregnancy among pregnant women at high risk of pre-eclampsia: A randomized clinical trial.

Zheng Lili (2020) · Pregnancy hypertension · n=1576

Supplementation with Small-Quantity Lipid-Based Nutrient Supplements Does Not Increase Child Morbidity in a Semiurban Setting in Ghana: A Secondary Outcome Noninferiority Analysis of the International Lipid-Based Nutrient Supplements (iLiNS)-DYAD Randomized Controlled Trial.

Adu-Afarwuah Seth (2020) · The Journal of nutrition

The Protective Effect of Maternal Folic Acid Supplementation on Childhood Cancer: A Systematic Review and Meta-analysis of Case-control Studies.

Wan Ismail Wan Rosmawati (2019) · Journal of preventive medicine and public health = Yebang Uihakhoe chi · n=17

Maternal and Infant Lipid-Based Nutritional Supplementation Increases Height of Ghanaian Children at 4-6 Years Only if the Mother Was Not Overweight Before Conception.

Kumordzie Sika M (2019) · The Journal of nutrition

Maternal-Infant Supplementation with Small-Quantity Lipid-Based Nutrient Supplements Does Not Affect Child Blood Pressure at 4-6 Y in Ghana: Follow-up of a Randomized Trial.

Kumordzie Sika M (2019) · The Journal of nutrition

Prenatal iron containing supplements provided to Chinese women with no or mild anemia had no effect on hemoglobin concentration in post-partum women or their infants at 6 and 12 months of age.

Serdula Mary K (2019) · European journal of clinical nutrition

Acceptability and Utilization of Three Nutritional Supplements during Pregnancy: Findings from a Longitudinal, Mixed-Methods Study in Niger.

Clermont Adrienne (2018) · Nutrients

Maternal folic acid supplementation for the prevention of preeclampsia: A systematic review and meta-analysis.

Bulloch Rhodi E (2018) · Paediatric and perinatal epidemiology

From the Field: Improving Fetal and Infant Growth in Vulnerable Populations.

Adu-Afarwuah Seth (2018) · Food and nutrition bulletin · n=1320

Short-term folinic acid supplementation and aerobic exercise improve vascular reactivity in HIV-infected individuals.

Grigoletti Shana S (2018) · HIV clinical trials

MTHFR A1298C polymorphisms reduce the risk of congenital heart defects: a meta-analysis from 16 case-control studies.

Yu Di (2017) · Italian journal of pediatrics

A Simplified Regimen Compared with WHO Guidelines Decreases Antenatal Calcium Supplement Intake for Prevention of Preeclampsia in a Cluster-Randomized Noninferiority Trial in Rural Kenya.

Omotayo Moshood O (2017) · The Journal of nutrition · n=990

Preconception Micronutrient Supplementation with Iron and Folic Acid Compared with Folic Acid Alone Affects Linear Growth and Fine Motor Development at 2 Years of Age: A Randomized Controlled Trial in Vietnam.

Nguyen Phuong H (2017) · The Journal of nutrition

Folic acid therapy reduces the risk of mortality associated with heavy proteinuria among hypertensive patients.

Li Youbao (2017) · Journal of hypertension

Biochemical, physiological and clinical effects of l-methylfolate in schizophrenia: a randomized controlled trial.

Roffman J L (2018) · Molecular psychiatry · n=55

Folic acid therapy reduces serum uric acid in hypertensive patients: a substudy of the China Stroke Primary Prevention Trial (CSPPT).

Qin Xianhui (2017) · The American journal of clinical nutrition · n=7685

Impact of Preconception Micronutrient Supplementation on Anemia and Iron Status during Pregnancy and Postpartum: A Randomized Controlled Trial in Rural Vietnam.

Nguyen Phuong H (2016) · PloS one · n=1813

Folic Acid Therapy Reduces the First Stroke Risk Associated With Hypercholesterolemia Among Hypertensive Patients.

Qin Xianhui (2016) · Stroke

Small-quantity, lipid-based nutrient supplements provided to women during pregnancy and 6 mo postpartum and to their infants from 6 mo of age increase the mean attained length of 18-mo-old children in semi-urban Ghana: a randomized controlled trial.

Adu-Afarwuah Seth (2016) · The American journal of clinical nutrition · n=1320

Sustained effects of small-quantity lipid-based nutrient supplements provided during the first 1000 days on child growth at 9-11 y in a randomized controlled trial in Ghana.

Bentil Helena J (2024) · The American journal of clinical nutrition · n=966

School-based supplementation with iron-folic acid or multiple micronutrient tablets to address anemia among adolescents in Burkina Faso: a cluster-randomized trial.

Cliffer Ilana R (2023) · The American journal of clinical nutrition

Folate deficiency among women of reproductive age in Ethiopia: A systematic review and meta-analysis.

Gebremichael Berhe (2023) · PloS one

Effect of Lipid-Based Multiple Micronutrients Supplementation in Underweight Primigravida Pre-Eclamptic Women on Maternal and Pregnancy Outcomes: Randomized Clinical Trial.

Sher Nabila (2022) · Medicina (Kaunas, Lithuania)

Effect of Picture-based health education and counselling on knowledge and adherence to preconception Iron-folic acid supplementation among women planning to be pregnant in Eastern Ethiopia: a randomized controlled trial.

Berhane Anteneh (2022) · Journal of nutritional science

Longitudinal Nutritional Intakes in Italian Pregnant Women in Comparison with National Nutritional Guidelines.

Lisso Fabrizia (2022) · Nutrients · n=176

Effectiveness of Health Information Package Program on Knowledge and Compliance among Pregnant Women with Anemia: A Randomized Controlled Trial.

Elsharkawy Nadia B (2022) · International journal of environmental research and public health · n=196

The Effects of Folic Acid Supplementation on Pro-inflammatory Mediators: a Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials.

Zargarzadeh Nikan (2021) · Clinical therapeutics · n=2286

Effects of Folic Acid Supplementation on Inflammatory Markers: A Grade-Assessed Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials.

Asbaghi Omid (2021) · Nutrients

Folic acid supplementation in postmenopausal women with hot flushes: phase III randomised double-blind placebo-controlled trial.

Ewies Aaa (2021) · BJOG : an international journal of obstetrics and gynaecology

The Association Between the Risk of Hypertensive Disorders of Pregnancy and Folic Acid: A Systematic Review and Meta-Analysis.

Yu Yahui (2021) · Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques · n=359041

Effects of prenatal micronutrients supplementation timing on pregnancy-induced hypertension: Secondary analysis of a double-blind randomized controlled trial.

Liu Yingying (2021) · Maternal & child nutrition

Beneficial effect of l-arginine in women using assisted reproductive technologies: a small-scale randomized controlled trial.

So Shuhei (2020) · Nutrition research (New York, N.Y.) · n=120

Effects of an Iodine-Containing Prenatal Multiple Micronutrient on Maternal and Infant Iodine Status and Thyroid Function: A Randomized Trial in The Gambia.

Eriksen Kamilla G (2020) · Thyroid : official journal of the American Thyroid Association

Provision of Lipid-Based Nutrient Supplements to Mothers During Pregnancy and 6 Months Postpartum and to Their Infants from 6 to 18 Months Promotes Infant Gut Microbiota Diversity at 18 Months of Age but Not Microbiota Maturation in a Rural Malawian Setting: Secondary Outcomes of a Randomized Trial.

Kamng'ona Arox W (2020) · The Journal of nutrition · n=869

The effects of supplementing maternal and infant diets with lipid-based nutrient supplements on physical activity and sedentary behaviour at preschool age in Ghana.

Ocansey Maku E (2019) · The British journal of nutrition · n=375

Impact of nutritional supplementation during pregnancy on antibody responses to diphtheria-tetanus-pertussis vaccination in infants: A randomised trial in The Gambia.

Okala Sandra G (2019) · PLoS medicine · n=875

Effects of folic acid supplementation on C-reactive protein: A systematic review and meta-analysis of randomized controlled trials.

Fatahi S (2019) · Nutrition, metabolism, and cardiovascular diseases : NMCD · n=1179

Prenatal and postnatal lipid-based nutrient supplementation and cognitive, social-emotional, and motor function in preschool-aged children in Ghana: a follow-up of a randomized controlled trial.

Ocansey Maku E (2019) · The American journal of clinical nutrition

The Effects of Folic Acid Supplementation on Recurrence and Metabolic Status in Endometrial Hyperplasia: A Randomized, Double-Blind, Placebo-Controlled Trial.

Bahmani Fereshteh (2018) · Archives of Iranian medicine · n=30

A Pilot Randomized Controlled Double-Blind Trial of High- Versus Low-Dose Weekly Folic Acid in People With Rheumatoid Arthritis Receiving Methotrexate.

Stamp Lisa K (2019) · Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases

Inadequate iron stores in early term neonates.

Hua Ying (2018) · Journal of perinatology : official journal of the California Perinatal Association

Effects of Weekly Iron and Folic Acid Supplements on Malaria Risk in Nulliparous Women in Burkina Faso: A Periconceptional, Double-Blind, Randomized Controlled Noninferiority Trial.

Gies Sabine (2018) · The Journal of infectious diseases · n=980

The Effects of Folate Supplementation on Diabetes Biomarkers Among Patients with Metabolic Diseases: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Akbari Maryam (2018) · Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · n=763

Effects of long-term weekly iron and folic acid supplementation on lower genital tract infection - a double blind, randomised controlled trial in Burkina Faso.

Brabin Loretta (2017) · BMC medicine · n=1954

Lipid-Based Nutrient Supplements During Pregnancy and Lactation Did Not Affect Human Milk Oligosaccharides and Bioactive Proteins in a Randomized Trial.

Jorgensen Josh M (2017) · The Journal of nutrition · n=647

Unmetabolized Folic Acid, Tetrahydrofolate, and Colorectal Adenoma Risk.

Rees Judy R (2017) · Cancer prevention research (Philadelphia, Pa.) · n=924

The effect of dietary folic acid on biochemical parameters and gene expression of three heat shock proteins (HSPs) of blunt snout bream (Megalobrama amblycephala) fingerling under acute high temperature stress.

Sesay Daniella Fatmata (2017) · Fish physiology and biochemistry

Lipid-based nutrient supplementation in the first 1000 d improves child growth in Bangladesh: a cluster-randomized effectiveness trial.

Dewey Kathryn G (2017) · The American journal of clinical nutrition · n=4011

Association of Folate Level in Blood with the Risk of Schizophrenia.

Ding Yujie (2017) · Combinatorial chemistry & high throughput screening

Effects of Two-Year Vitamin B12 and Folic Acid Supplementation on Depressive Symptoms and Quality of Life in Older Adults with Elevated Homocysteine Concentrations: Additional Results from the B-PROOF Study, an RCT.

de Koning Elisa J (2016) · Nutrients · n=2919

Association of prenatal lipid-based nutritional supplementation with fetal growth in rural Gambia.

Johnson William (2017) · Maternal & child nutrition

Folic Acid Supplementation and the Risk of Cardiovascular Diseases: A Meta-Analysis of Randomized Controlled Trials.

Li Yanping (2016) · Journal of the American Heart Association · n=334

Low-dose daily folic acid (400 μg) supplementation does not affect regulation of folate transporters found present throughout the terminal ileum and colon of humans: a randomized clinical trial.

Farrell Colleen C (2024) · The American journal of clinical nutrition

Supplementation with (6S)-5-methyltetrahydrofolic acid appears as effective as folic acid in maintaining maternal folate status while reducing unmetabolised folic acid in maternal plasma: a randomised trial of pregnant women in Canada.

Cochrane Kelsey M (2024) · The British journal of nutrition

Improving coverage of antenatal iron and folic acid supplementation and malaria prophylaxis through targeted information and home deliveries in Côte d'Ivoire: a cluster randomised controlled trial.

Koné Siaka (2023) · BMJ global health

Effects of antenatal micronutrient supplementation regimens on adolescent emotional and behavioral problems: A 14-year follow-up of a double-blind, cluster-randomized controlled trial.

Zhu Zhonghai (2023) · Clinical nutrition (Edinburgh, Scotland)

Association between prenatal provision of lipid-based nutrient supplements and caesarean delivery: Findings from a randomised controlled trial in Malawi.

Salenius Meeri (2022) · Maternal & child nutrition · n=1391

Prenatal fortified balanced energy-protein supplementation and birth outcomes in rural Burkina Faso: A randomized controlled efficacy trial.

de Kok Brenda (2022) · PLoS medicine · n=22

The effect of blister packaging Iron and Folate on adherence to medication and hemoglobin levels among pregnant women at National Referral Hospital antenatal clinics in a low to middle income country: a Randomised Controlled Trial (The IFAd Trial).

Byamugisha Josaphat (2022) · BMC pregnancy and childbirth · n=474

Neurodevelopmental effects of maternal folic acid supplementation: a systematic review and meta-analysis.

Chen Hanxiao (2023) · Critical reviews in food science and nutrition

Biological and clinical effects of a resveratrol-based multivitamin supplement on intracytoplasmic sperm injection cycles: a single-center, randomized controlled trial.

Gerli Sandro (2022) · The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · n=101

The Inclusion of Folic Acid in Weekly Iron-Folic Acid Supplements Confers no Additional Benefit on Anemia Reduction in Nonpregnant Women: A Randomized Controlled Trial in Malaysia.

Samson Kaitlyn L I (2021) · The Journal of nutrition

Homocysteine and female fertility, pregnancy loss and offspring birthweight: a two-sample Mendelian randomization study.

Kjaergaard Alisa D (2022) · European journal of clinical nutrition

Efficacy of Oral Vitamin Supplementation in Inflammatory Rheumatic Disorders: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Nguyen Yann (2020) · Nutrients

The impact of myo-inositol supplementation on sleep quality in pregnant women: a randomized, double-blind, placebo-controlled study.

Mashayekh-Amiri Sepideh (2022) · The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · n=60

The efficacy and safety of panitumumab supplementation for colorectal cancer: A meta-analysis of randomized controlled studies.

Wang Chengchen (2020) · Medicine

Micronutrients in support to the one carbon cycle for the modulation of blood fasting homocysteine in PCOS women.

Schiuma N (2020) · Journal of endocrinological investigation

The effect of folic acid in patients with cardiovascular disease: A systematic review and meta-analysis.

Wang Yuan (2019) · Medicine · n=47523

Nutrient supplementation during the first 1000 days and growth of infants born to pregnant adolescents.

Dewey Kathryn G (2020) · Annals of the New York Academy of Sciences · n=4011

Exposure to a slightly sweet lipid-based nutrient supplement during early life does not increase the level of sweet taste most preferred among 4- to 6-year-old Ghanaian children: follow-up of a randomized controlled trial.

Okronipa Harriet (2019) · The American journal of clinical nutrition

Effect of a weight-loss stabilization following a weight reduction with or without meal replacement on cardiometabolic risk in overweight women. A randomized controlled trial.

Armborst Deborah (2019) · International journal of food sciences and nutrition

Effect of long-term low-dose folic acid supplementation on degree of total homocysteine-lowering: major effect modifiers.

Wang Binyan (2018) · The British journal of nutrition · n=867

Supplementation of folic acid in pregnancy and the risk of preeclampsia and gestational hypertension: a meta-analysis.

Liu Cheng (2018) · Archives of gynecology and obstetrics · n=149320

Effect of life skills building education and micronutrient supplements provided from preconception versus the standard of care on low birth weight births among adolescent and young Pakistani women (15-24 years): a prospective, population-based cluster-randomized trial.

Baxter Jo-Anna B (2018) · Reproductive health

Risk of basal cell carcinoma in a randomized clinical trial of aspirin and folic acid for the prevention of colorectal adenomas.

Passarelli M N (2018) · The British journal of dermatology · n=1121

The effects of folate supplementation on lipid profiles among patients with metabolic diseases: A systematic review and meta-analysis of randomized controlled trials.

Tabrizi Reza (2018) · Diabetes & metabolic syndrome

Response of Red Blood Cell Folate to Supplementation in Nonpregnant Women is Predictable: A Proposal for Personalized Supplementation.

Obeid Rima (2018) · Molecular nutrition & food research · n=119

Trial of ready-to-use supplemental food and corn-soy blend in pregnant Malawian women with moderate malnutrition: a randomized controlled clinical trial.

Callaghan-Gillespie Meghan (2017) · The American journal of clinical nutrition

Lack of association between MTHFR A1298C polymorphism and outcome of methotrexate treatment in rheumatoid arthritis patients: evidence from a systematic review and meta-analysis.

Fan Hongqiong (2017) · International journal of rheumatic diseases

Effect of 12-month intervention with lipid-based nutrient supplement on the physical activity of Malawian toddlers: a randomised, controlled trial.

Pulakka A (2017) · The British journal of nutrition

Maternal Supplementation with Small-Quantity Lipid-Based Nutrient Supplements Compared with Multiple Micronutrients, but Not with Iron and Folic Acid, Reduces the Prevalence of Low Gestational Weight Gain in Semi-Urban Ghana: A Randomized Controlled Trial.

Adu-Afarwuah Seth (2017) · The Journal of nutrition · n=1320

Maternal multiple micronutrient supplementation and other biomedical and socioenvironmental influences on children's cognition at age 9-12 years in Indonesia: follow-up of the SUMMIT randomised trial.

Prado Elizabeth L (2017) · The Lancet. Global health · n=19

Is folic acid supplementation useful for chronic kidney disease?

Bravo-Soto Gonzalo A (2016) · Medwave

Effects of prenatal micronutrient and early food supplementation on metabolic status of the offspring at 4.5 years of age. The MINIMat randomized trial in rural Bangladesh.

Ekström Eva-Charlotte (2016) · International journal of epidemiology

Effect of vitamin D3 supplementation on iron status: a randomized, double-blind, placebo-controlled trial among ethnic minorities living in Norway.

Madar Ahmed A (2016) · Nutrition journal · n=251