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Not recommended

Human studies show no meaningful benefit, potential harm, or the risks outweigh any possible upside. Better alternatives exist.

GABA

Also known as: gamma-aminobutyric acid, pharmaGABA

EEvidence Against00 studies referenced

Stress management Sleep & recovery Mental health & wellbeing

Common dosage

100-750mg daily

Description

Primary inhibitory neurotransmitter. Supplemental GABA may promote relaxation and sleep, though debate exists about blood-brain barrier crossing. PharmaGABA (natural fermentation) may be more effective than synthetic.

Safety & interactions

Generally safe. May cause drowsiness. Start low (100mg). Avoid combining with sedatives or anti-anxiety medications.

Check interactions with other supplements→

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Recommended: 100-750mg daily

Questions about GABA

Are there any known interactions between GABA and common medications?

How quickly does GABA start working and should I cycle it?

Who should avoid GABA, including during pregnancy or breastfeeding?