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Vitamin C

Also known as: ascorbic acid, sodium ascorbate

AAdequate Evidence75/10019 studies referenced

Common dosage

500-1000mg daily

Category

vitamin

Description

Antioxidant vitamin supporting immune function, collagen synthesis, and iron absorption. Benefits are most pronounced in those under physical stress.

Safety & interactions

May cause GI upset at high doses. Liposomal form has better absorption.
Check all interactions →

What the research shows

May help reduce cholesterol and triglyceride levels in people with diabetes or on dialysis

Could slightly lower blood pressure, with a modest reduction of about 3-4 mmHg in some people

emerging evidence1 study:Food & function (2026)

May help reduce insulin resistance in people with type 2 diabetes through its antioxidant properties

emerging evidence1 study:Nutrition reviews (2026)

Could help reduce symptoms of restless legs syndrome and improve iron function in dialysis patients

May reduce muscle damage and speed recovery after intense exercise

emerging evidence1 study:Clinical nutrition ESPEN (2026)

Might help lower the risk of preterm birth during pregnancy when combined with vitamin E

Does not significantly affect blood pressure overall, and shows no clear benefit for inflammation markers despite being an antioxidant

Evidence is mixed and insufficient to recommend routine supplementation in dialysis patients for reducing chronic inflammation

Researched health areas

Health domains where Vitamin C has published research. Click any domain to see all supplements and habits for that area.

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Questions about Vitamin C

Studies on Vitamin C (19)

ProtocolEngine provides general health information based on published research. This is not medical advice. Consult a healthcare professional before starting any supplement or health protocol.