Vitamin B Complex

Radiofrequency Ablation and Chemotherapy vs Chemotherapy Only in Locally Advanced Pancreatic Cancer: The PELICAN Randomized Clinical Trial.

Seelen Leonard W F (2026) · JAMA network open · n=188

Atezolizumab plus FOLFOX for Stage III Mismatch Repair-Deficient Colon Cancer.

Sinicrope Frank A (2026) · The New England journal of medicine · n=355

A Randomized Trial of Encorafenib and Cetuximab Versus Irinotecan/Cetuximab or FOLFIRI/Cetuximab in Chinese Patients With BRAFV600E Mutant Metastatic Colorectal Cancer: The NAUTICAL Study.

Xicheng Wang (2026) · Cancer medicine

Spina bifida in Africa: A systematic review and Meta-Analysis of Presentation, Management, and outcomes.

O'Leary Sean (2026) · Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia · n=4779

Prevalence of Congenital Abnormalities in Abortuses and Stillbirths in India: A Systematic Review and Meta-Analysis.

Das Sushant Swaroop (2026) · Congenital anomalies · n=2024

Complex Effects of B-Vitamin Combinations on Cardiovascular Diseases: A Systematic Review and Meta-Analysis of Randomized Controlled Trials over Three Decades.

Ren Ruodi (2026) · Nutrients · n=68363

First-line modified FOLFOX plus/minus nivolumab and Ipilimumab or FLOT plus nivolumab in advanced gastroesophageal adenocarcinoma: a phase II multi-cohort trial.

Lorenzen Sylvie (2026) · Nature communications

Vitamin E TPGS-enhanced riboflavin accelerated transepithelial cross-linking versus accelerated epithelium-off protocol in progressive keratoconus: a prospective randomized trial.

Jain Parul (2026) · International ophthalmology

NALIRIFOX versus nab-paclitaxel and gemcitabine in older patients with treatment-naive metastatic pancreatic cancer: a subgroup analysis of the pivotal NAPOLI 3 trial.

Macarulla T (2026) · ESMO open · n=275

Meta-analysis of the uncultured gut microbiome across 11,115 global metagenomes reveals a candidate signature of health.

da Silva Ana C (2026) · Cell host & microbe

A randomized clinical trial assessing the efficacy of vitamin B prophylaxis in attenuating paclitaxel-induced neuropathy and the imperative use of gabapentin in diabetic ovarian cancer patients.

Haggagy Mahitab (2026) · Medical oncology (Northwood, London, England)

Effectiveness of alpha lipoic acid supplementation on biochemical, clinical, and inflammatory parameters in patients with diabetic polyneuropathy: A systematic review and meta-analysis.

Salinas Ayline Vergara (2026) · Diabetes & metabolic syndrome

Effects of Ziziphus jujuba, metformin, and myoinositol on pregnancy rates and metabolic parameters in infertile women with PCOS: a randomized controlled trial.

Mashhadi Faezeh (2026) · Journal of ovarian research · n=49

A Meta-Analysis of the Effects of Homocysteine-Lowering Therapy on Chronic Kidney Disease.

Lin Hua (2026) · Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · n=23638

Combined B-vitamin supplementation on homocysteine and vascular outcomes in coronary heart disease: a meta-analysis.

Guo Liping (2026) · Annals of medicine · n=14539

Folic acid fortification of iodized salt improves the folate status of nonpregnant adult Ethiopian females and does not impair their iodine status: a community-based, household-randomized, dose-response trial.

Tessema Masresha (2026) · The American journal of clinical nutrition

Thromboembolic Events During Perioperative Therapy for Resectable and Borderline Resectable Pancreatic Cancer in the PREOPANC-2 Trial.

Willems Ruth A L (2026) · Journal of clinical oncology : official journal of the American Society of Clinical Oncology · n=325

Hydroxocobalamin, thiamine, and pyridoxine as an adjunct to standard treatment in chronic low back pain: a randomized clinical trial.

Reyes-Alvarez Maria Teresa (2026) · Medicina clinica · n=81

Efficacy of L-methylfolate and methylcobalamin in treating resistant hypertension associated with elevated serum homocysteine in hemodialysis patients.

Salem Mohamed Sherif (2026) · BMC nephrology

SLOG versus modified FOLFIRINOX as first-line treatment for advanced pancreatic cancer: A randomized phase II trial (TCOG T5217).

Chiang Nai-Jung (2026) · European journal of cancer (Oxford, England : 1990) · n=129

Effects of benfotiamine treatment over 12 months on morphometric, neurophysiological and clinical measures in type 2 diabetes patients with symptomatic polyneuropathy: a randomized, placebo-controlled, double-blind clinical trial (BOND study).

Ziegler Dan (2026) · BMJ open diabetes research & care · n=57

Efficacy of Oral Vitamin B-12 at 1000 μg Compared with 2000 μg on Neuropathic Outcomes in Patients with Diabetic Peripheral Neuropathy and Low Serum Vitamin B-12: a Randomized Clinical Trial.

Mansour Asieh (2026) · The Journal of nutrition · n=35

NALIRIFOX versus gemcitabine plus nab-paclitaxel in Chinese patients with advanced pancreatic adenocarcinoma: a randomized, open-label phase II trial.

Gao Chuntao (2026) · Nature communications · n=117

Feasibility of a randomized clinical trial comparing 5-methyltetrahydrofolate and folic acid prenatal multivitamins in couples with recurrent pregnancy loss.

Ledowsky Carolyn (2026) · Nutrition research (New York, N.Y.)

The differential impact of three different NAD+ boosters on circulatory NAD and microbial metabolism in humans.

Christen Stefan (2026) · Nature metabolism

The BEVATOMOX phase II trial: raltitrexed/oxaliplatin/bevacizumab vs mFOLFOX6/bevacizumab in 2nd-line metastatic colorectal cancer.

Samalin Emmanuelle (2026) · The oncologist · n=62

A Phase II Trial of an Extended-Release siRNA Implant Targeting KRASG12D/V in Locally Advanced Pancreatic Cancer.

Alagesan Brinda (2026) · Clinical cancer research : an official journal of the American Association for Cancer Research · n=1

[Pathogenetic and therapeutic approaches to the correction of neurocognitive disorders in patients with chronic brucellosis].

Shuldyakov A A (2025) · Terapevticheskii arkhiv · n=40

Improved HDL, LDL and total cholesterol levels following a 3-month administration of Mentha spicata leaf extract and Amaranthus caudatus seed flour extracts, flavonoids and B vitamins. A placebo-controlled, double-blind, randomized clinical trial.

Di Minno Alessandro (2026) · Nutrition, metabolism, and cardiovascular diseases : NMCD · n=114

Upfront Modified FOLFOXIRI Plus Panitumumab for RAS/BRAF Wild-Type Metastatic Colorectal Cancer: Final Results of the Phase III TRIPLETE Study.

Conca Veronica (2026) · Journal of clinical oncology : official journal of the American Society of Clinical Oncology · n=217

Evaluation of Nicotinamide Riboside in Prevention of Small Nerve Fiber Axon Degeneration and Promotion of Nerve Regeneration.

Thomas Simone (2026) · Journal of the peripheral nervous system : JPNS

Altered gut microbiome function in ADHD: More Prevotella, less vitamin B12 biosynthesis, and beneficial modulation by synbiotic treatment.

Stiernborg Miranda (2026) · Brain, behavior, and immunity · n=147

Effect of Myo-Inositol Treatment on Serum Asprosin Levels of Pregnant Women: A Prospective Randomized Controlled Pilot Study.

Özay Ali Cenk (2025) · Journal of pregnancy · n=40

Endothelial sensitivity to exercise-induced shear rate in older adults: effect of biological sex and acute folic acid consumption.

Oubouchou Katia (2026) · American journal of physiology. Heart and circulatory physiology

Deep Learning-Derived Sarcopenia Marker Predicts Benefit from Anti-EGFR Therapy in Patients with RAS Wild-type Metastatic Colorectal Cancer.

Keyl Julius (2026) · Clinical cancer research : an official journal of the American Association for Cancer Research · n=248

Rapid and Visible Efficacy of a Dermocosmetic in Acne Patients With Fair Skin Phototypes: Results of a Randomized Split-Face Study.

Queille-Roussel Catherine (2026) · Journal of cosmetic dermatology · n=16

Nutritional status-dependent DNA methylation modifications on adipose tissue in systemic lupus erythematosus women following folic acid and vitamin B12 supplementation: a randomized double-blind placebo-controlled trial.

da Mota Jhulia C N L (2026) · Clinical epigenetics

Clinical safety of ultra-high-dose methylcobalamin in patients with amyotrophic lateral sclerosis: Open-label extension of a phase 2/3 randomized controlled study.

Kaji Ryuji (2026) · Journal of the neurological sciences · n=144

Impact of Mandatory Grain Fortification With Folic Acid on Population Folate Concentrations and the Risk of Folate Deficiency and Insufficiency: A Systematic Review and Meta-Analysis.

Parker Jessica (2026) · The Journal of nutrition

The Effect of Vitamin B-12 Supplementation During Pregnancy on Early Motor Performance: Secondary Analyses From a Double-Blinded Randomized Controlled Trial.

Kvestad Ingrid (2026) · The Journal of nutrition

Impact evaluation of a population-based 'Screen and Treat for Anaemia Reduction (STAR)' strategy: a cluster randomised trial in rural Telangana, India.

Pullakhandam Raghu (2025) · BMJ global health · n=6131

Folate Intake and Breast Cancer Risk: A Systematic Review and Meta-Analysis.

Eleotério Mariana Reis (2026) · Molecular nutrition & food research · n=8

ctDNA Detection with Low-Pass Whole-Genome Bisulfite Sequencing in RAS Wild-Type Metastatic Colorectal Cancer: An Exploratory Objective of the VALENTINO Trial.

Manca Paolo (2026) · Clinical cancer research : an official journal of the American Association for Cancer Research · n=154

Mapping the burden prevalence of neural tube defects across Indian regions: a systematic review and meta-analysis.

Sinha Urmila (2025) · The Pan African medical journal

Global prevalences of erythropoiesis-associated micronutrient deficiencies (iron, folate, and vitamin B12) among pregnant women: a systematic review and meta-analysis.

Nguyen Nhi Thi Hong (2025) · Annals of medicine

Impact of Alpha Lipoic Acid as an Adjuvant Therapy on Inflammation and Fibrosis in Type 2 Diabetic Patients with Ischemic Cardiomyopathy: A Randomized Controlled Trial.

Shama Aya M (2026) · Journal of dietary supplements · n=67

The effectiveness and safety of the active form of folate on biochemical parameters in women of childbearing age: A systematic review and meta-analysis.

Xie Min (2025) · Medicine

Intergroup randomized phase III study of adjuvant FOLFIRI, FOLFOX, or 5-FU/leucovorin for stage II/III rectal cancer: ECOG-ACRIN E3201.

Kam Audrey E (2025) · The oncologist · n=3150

Asciminib demonstrates superior efficacy and safety in newly diagnosed chronic myeloid leukemia in the ASC4FIRST trial.

Cortes Jorge E (2026) · Blood · n=3

A randomized Phase 1b trial evaluating the pharmacodynamics of ilofotase alfa in adults with hypophosphatasia.

Seefried Lothar (2026) · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · n=12

Hepatectomy Plus Chemotherapy or Chemotherapy Alone for Resectable Liver and Unresectable Lung Metastases from Colorectal Adenocarcinoma (LUNA): A Randomized Phase II Trial.

Folkert Ian W (2026) · Annals of surgical oncology · n=10

Effect of Insulin Sensitizers on Glycemic and Lipid Profile in Patients with Polycystic Ovary Syndrome (PCOS).

Stevchevska Aleksandra (2025) · Prilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki)

Predictive Role of Circulating Tumor DNA in Stage III Colon Cancer Treated With Celecoxib: A Post Hoc Analysis of the CALGB (Alliance)/SWOG 80702 Phase 3 Randomized Clinical Trial.

Zhang George Q (2026) · JAMA oncology · n=940

The protective effects of Nicorandil on renal function in patients undergoing coronary interventions: a systematic review and meta-analysis.

Abo Elnaga Ahmed A (2025) · BMC nephrology · n=2837

Impact of sex on efficacy and safety of 1st-line treatment with FOLFIRI plus cetuximab or bevacizumab in RAS/BRAF wildtype metastatic colorectal cancer - A subgroup analysis of the FIRE-3 (AIO KRK-0306) trial.

Heinrich Kathrin (2026) · European journal of cancer (Oxford, England : 1990) · n=352

Enhancing Facial Rejuvenation Outcomes With a Novel Retinaldehyde-Based Cream: A Comparative Randomized Intra-Individual Study.

Monteil Camille (2025) · Journal of cosmetic dermatology · n=66

Thiamin supplementation on mitigating kidney injury and mortality in patients with septic shock: A systematic review and meta-analysis of randomized controlled trials.

Wang Guizuo (2026) · Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · n=438

Preoperative mFOLFIRINOX versus PAXG for stage I-III resectable and borderline resectable pancreatic ductal adenocarcinoma (PACT-21 CASSANDRA): results of the first randomisation analysis of a randomised, open-label, 2 × 2 factorial phase 3 trial.

Reni Michele (2026) · Lancet (London, England) · n=132

Associations of antenatal micronutrient supplementation with adolescent blood pressure: evidence from a 14-year follow-up study of a randomized controlled trial.

Feng Huilan (2025) · BMC public health

[Results of the observational program CITOTREK (use of the drug CITOflavin in Tablets) in patients with tension headaches against the backgRound of asthenic syndromE taKing into account comorbidity].

Putilina M V (2025) · Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova · n=150

Low Bioavailability and High TMAO Production: Novel Insights Into Acetylcarnitine and Carnitine Metabolism.

Krims-Davis Kristaps (2025) · Molecular nutrition & food research

Isolating the effects of carbohydrate and lipid availability on exercise-induced skeletal muscle signalling in males.

Bradshaw Louise (2026) · The Journal of physiology

Vitamin B supplementation enhances the efficacy of non-steroidal anti-inflammatory drugs in patients with painful foot and ankle conditions: A multicenter, prospective, randomized controlled trial.

Song Myung-Geun (2025) · PloS one · n=201

Relationship between [18F]PSMA-1007 PET parameters and biochemical recurrence-free survival in high-risk prostate cancer patients receiving neoadjuvant hormonal treatment.

Ahmadi Bidakhvidi Niloefar (2026) · European journal of nuclear medicine and molecular imaging

The role of oral alpha-lipoic acid as an adjuvant antioxidant therapy in diabetic nephropathy among children and adolescents with type 1 diabetes: a randomized controlled trial.

Elhenawy Yasmine Ibrahim (2026) · Journal of diabetes and its complications · n=50

TRYBECA-1: A Randomized Phase III Study of Eryaspase Combined With Chemotherapy Versus Chemotherapy as Second-Line Treatment in Patients With Advanced Pancreatic Adenocarcinoma.

Hammel Pascal (2025) · Journal of clinical oncology : official journal of the American Society of Clinical Oncology · n=255

Effect of prenatal multiple micronutrient supplements and medium-quantity lipid-based nutritional supplements on maternal weight gain and infant birth weight in rural Niger: a cluster-randomised trial.

Rattigan Susan M (2025) · BMJ global health · n=53

The effect of facility-based nutrition education and counseling on dietary intake and supplemental iron folic acid use among pregnant women: a cluster randomised controlled trial.

Mohammedsanni Afrah (2025) · Public health nutrition

Serum Vitamin A Is Associated with Variations in the Relationship between Plasma B6 Vitamers and Cardiovascular Disease Risk.

Dhar Indu (2026) · The Journal of nutrition · n=4091

Effects of nicotinamide supplementation in normal-tension glaucoma: a crossover placebo-controlled randomised clinical trial.

Ha Ahnul (2026) · The British journal of ophthalmology

Negative hyperselection of patients with stage III colon cancer receiving anti-EGFR-based adjuvant treatment.

Ambrosini M (2025) · ESMO open

Eight-year results of LASIK with or without combined accelerated crosslinking in highly myopic eyes.

Kaiser Klemens Paul (2026) · Journal of cataract and refractive surgery · n=13

A Randomized Controlled Trial of Stereotactic Body Radiation Therapy Versus Chemoradiation Following Induction Chemotherapy in Borderline Resectable and Locally Advanced Pancreatic Cancer.

Thakur Vandana (2025) · Journal of gastrointestinal cancer

Clinical study on the treatment of leukopenia after chemotherapy with leucogen tablets and Shengbai mixture.

Zeng Yuxiao (2025) · Pakistan journal of pharmaceutical sciences · n=96

Patient-reported outcomes with paclitaxel and ramucirumab switch maintenance in advanced gastroesophageal cancer: A secondary endpoint of the ARMANI phase 3 trial.

Cristarella Eleonora (2025) · European journal of cancer (Oxford, England : 1990) · n=280

Perfusion Assessment in CEUS Imaging for Estimating Pancreatic Cancer Response to Sonoporation-Enhanced Chemotherapy.

Adler Omri (2026) · Ultrasonic imaging · n=13

Antifungal prophylaxis in patients with FMS-like tyrosine kinase 3-internal tandem duplication (FLT3-ITD)-positive acute myeloid leukaemia receiving sorafenib during initial induction and consolidation treatment in ALLG AMLM16 trial.

Neoh Chin Fen (2025) · The Journal of antimicrobial chemotherapy · n=94

Efficacy of [18F]PSMA-1007 PET/CT in Primary Staging of Prostate Carcinoma: A Systematic Review and Metaanalysis.

Rahbar Kambiz (2026) · Journal of nuclear medicine : official publication, Society of Nuclear Medicine · n=739

Riboflavin supplements for blood pressure lowering in adults.

Bradbury Kathryn E (2025) · The Cochrane database of systematic reviews · n=320

Domvanalimab and zimberelimab in advanced gastric, gastroesophageal junction or esophageal cancer: a phase 2 trial.

Janjigian Yelena Y (2025) · Nature medicine

Plasma folate dynamics in Plasmodium falciparum-infected African children treated with artemisinin combination therapy and single low-dose primaquine or placebo.

Ajayi Seun (2025) · Malaria journal

Effects of alpha-lipoic acid supplementation on cardiometabolic risk factors: A systematic review and dose-response meta-analysis.

Mohammadi Shooka (2026) · Nutrition, metabolism, and cardiovascular diseases : NMCD

Neoadjuvant nab-paclitaxel plus gemcitabine followed by modified FOLFIRINOX for resectable pancreatic cancer: A randomized phase 3 trial.

Bai Xueli (2025) · Cancer cell · n=324

PREVENTION OF PACLITAXEL-INDUCED MOTOR NEUROPATHY OF FIBULAR AND TIBIAL NERVES WITH ALPHA-LIPOIC ACID AND IPIDACRIN HYDROCHLORIDE IN BREAST CANCER PATIENTS.

Holotiuk I (2025) · Experimental oncology · n=50

Factors influencing locoregional recurrence rates in locally advanced rectal cancer after total neoadjuvant treatment versus chemoradiotherapy in the RAPIDO trial.

Prata Ilaria (2025) · The British journal of surgery · n=920

A prospective study of serum folate levels in patients with solid tumors treated with olaparib.

Shammo Jamile (2025) · The oncologist

The effects of small-quantity lipid-based nutrient supplements on adolescent physical activity and sedentary behaviour: a follow-up of the International Lipid-Based Nutrient Supplements-DYAD-Ghana trial.

Fajardo Jonnatan (2025) · The British journal of nutrition

[Preoperative short-course radiotherapy followed by chemotherapy and PD-1 inhibitor administration for locally advanced rectal cancer: the initial results of a randomized controlled clinical trial (STELLAR II)].

Li H Y (2025) · Zhonghua zhong liu za zhi [Chinese journal of oncology] · n=52

Efficacy of B Vitamin Supplementation on Global Cognitive Function in Older Adults: A Systematic Review and Meta-analysis.

Berg Jade (2025) · Nutrition reviews · n=5275

Folic acid supplementation improves cognitive function in participants with cerebral small vascular disease-related cognitive impairment: a randomized controlled trial.

Liu Yinyue (2026) · The journal of prevention of Alzheimer's disease

Neoadjuvant FOLFIRINOX versus neoadjuvant gemcitabine-based chemoradiotherapy in resectable and borderline resectable pancreatic cancer (PREOPANC-2): a multicentre, open-label, phase 3 randomised trial.

Janssen Quisette P (2025) · The Lancet. Oncology · n=188

The effect of milk fat globule membrane phospholipid supplementation on cognitive function in older adults with subjective memory complaints-a randomized, double-blind, placebo-controlled trial.

Zajac Ian T (2025) · The American journal of clinical nutrition · n=263

Effect of methylcobalamin on capecitabine induced hand-foot syndrome in patients with HER2 negative early breast cancer: multicentre, double blind, randomised, placebo controlled, phase 3 trial.

Xia Yuan (2025) · BMJ (Clinical research ed.) · n=117

PASS-01: Randomized Phase II Trial of Modified FOLFIRINOX Versus Gemcitabine/Nab-Paclitaxel and Molecular Correlatives for Previously Untreated Metastatic Pancreatic Cancer.

Knox Jennifer J (2025) · Journal of clinical oncology : official journal of the American Society of Clinical Oncology · n=160

Myo-inositol Supplementation to Prevent Pregnancy Complications in Polycystic Ovary Syndrome: A Randomized Clinical Trial.

van der Wel Anne W T (2025) · JAMA · n=464

Pyridoxine supplementation for levetiracetam-related neuropsychiatric adverse events in pediatric and adolescent epilepsy: a prospective, double-blind, randomized, placebo-controlled trial.

Thananowan Pavida (2025) · Epilepsy & behavior : E&B · n=102

Primary tumor sidedness and negative hyperselection to modulate anti-EGFR-based maintenance strategies in patients with RAS wild-type metastatic colorectal cancer: individual patient data pooled analysis of two randomized clinical trials.

Ballhausen Alexej (2025) · British journal of cancer · n=607

Outcomes for FOLFIRI plus bevacizumab or cetuximab in patients treated with oxaliplatin-based adjuvant therapy: A combined analysis of FIRE-3 and CALGB/SWOG 80405 (Alliance).

Battaglin Francesca (2025) · European journal of cancer (Oxford, England : 1990) · n=800

Exploring the Link of Serum Vitamin B12, Folate, and Homocysteine Concentrations in Individuals with Multiple Sclerosis: An Umbrella Meta-analysis of Case-control Studies.

Abbasi Hamid (2025) · Neuroscience

Dietary diversity as a modifier of the effect of supplementation with multiple micronutrients during pregnancy on low birth weight in a randomized controlled trial in Bangladesh.

de Boer Mary (2025) · The American journal of clinical nutrition

Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study.

Gao Meiyan (2025) · Journal of cosmetic dermatology · n=60

Comparing Folic Acid Interventions and Arsenic Reduction Strategies for Neural Tube Defect Prevention in Bangladesh: A Systematic Review and Decision Analysis.

Wei Chih-Fu (2025) · Birth defects research

Comparison of Neoadjuvant Chemotherapy With FLOT and Modified DCF Regimens in Nonmetastatic Gastric Adenocarcinoma.

Pourghasemian Mehdi (2025) · Cancer reports (Hoboken, N.J.) · n=90

Asciminib in patients with newly diagnosed chronic myeloid leukemia: results from the Japanese subgroup of ASC4FIRST.

Takahashi Naoto (2025) · International journal of hematology

Accelerated Epithelium-off Corneal Cross-linking With Preservation of a Central Epithelial Island in the Management of Paracentral Progressive Keratoconus: A Comparative Clinical Trial.

Khalil Ahmad S (2025) · Journal of refractive surgery (Thorofare, N.J. : 1995) · n=77

Role of nicorandil in preventing contrast-induced nephropathy in patients undergoing cardiac catheterization procedures: an updated systematic review and meta-analysis.

Khan Ahmed Ali (2025) · International urology and nephrology · n=2931

The effects of methyl nutrients on cognition and one carbon metabolism in older adults with mild cognitive impairment, A systematic review and meta-analysis.

Zhao Yan (2025) · Geriatric nursing (New York, N.Y.)

Effect of high and low molecular weight sodium hyaluronic acid eye drops on corneal recovery after crosslinking in keratoconus patients.

Özkan Gamze (2025) · BMJ open ophthalmology · n=55

Pharmacokinetic and pharmacodynamic assessment of oral nicotinamide in the NEAT clinical trial for early Alzheimer's disease.

Ketron Gabriel L (2025) · Alzheimer's research & therapy · n=23

The ameliorative effect of myo-inositol on apoptosis-related genes expression in cumulus cells of women with polycystic ovary syndrome undergoing ICSI and its relationship with the quality of oocyte and embryo.

Yazdanpanah Zeynab (2025) · Naunyn-Schmiedeberg's archives of pharmacology

Randomized controlled trial of bromelain and alpha-lipoic acid in breast conservative surgery.

Sgaramella L I (2025) · Scientific reports

Folic acid supplementation during preconception period in sub-Saharan African countries: A systematic review and meta-analysis.

Aweke Mekuriaw Nibret (2025) · PloS one · n=12562

TangBi Formula for Painful Diabetic Distal Symmetric Polyneuropathy: A Multicenter, Randomized, Double-Blind, Placebo-Controlled and Parallel-Group Trial.

Zhao Xuefei (2025) · Journal of diabetes · n=188

Topical riboflavin versus 5-aminolevulinic acid photodynamic therapy for the treatment of mild to moderate acne: A split-face randomized study.

Ding Aijia (2025) · Photodiagnosis and photodynamic therapy · n=30

The Oral Bioavailability of Vitamin B12 at Different Doses in Healthy Indian Adults.

Kashyap Sindhu (2024) · Nutrients

Folate and vitamin B12 supplementation in patients with schizophrenia and low serum folate level: A 24-week randomized, double-blind, placebo-controlled study.

Chen Chun-Hsin (2026) · Journal of the Formosan Medical Association = Taiwan yi zhi

Effect of remote ischemic preconditioning, nicorandil, and trimetazidine in contrast-induced nephropathy: a network meta-analysis of randomized controlled trials.

Gao Hanchao (2024) · Renal failure

Olverembatinib After Failure of Tyrosine Kinase Inhibitors, Including Ponatinib or Asciminib: A Phase 1b Randomized Clinical Trial.

Jabbour Elias (2025) · JAMA oncology · n=60

Inflammatory Stress Determines the Need for Chemotherapy in Patients with HER2-Positive Esophagogastric Adenocarcinoma Receiving Targeted Therapy and Immunotherapy.

Tintelnot Joseph (2025) · Cancer immunology research

Modified FOLFOX6 with Cetuximab versus with Radiotherapy in Neoadjuvant Treatment of Locally Advanced Rectal Cancer: A Single-Center, Prospective, Randomized Controlled Trial.

Liu Chuanyuan (2024) · Biological & pharmaceutical bulletin · n=80

Efficacy and Safety of HAIC-FOLFOX Plus Tyrosine Kinase Inhibitors and Immune Checkpoint Inhibitors as First-line Treatment for Unresectable Advanced Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis.

Jiang Peng (2025) · Academic radiology · n=1072

Periconceptional folic acid supplementation for women with epilepsy: A systematic review of the literature.

Peng Anjiao (2024) · Epilepsy & behavior : E&B

Irinotecan hydrochloride liposome HR070803 in combination with 5-fluorouracil and leucovorin in locally advanced or metastatic pancreatic ductal adenocarcinoma following prior gemcitabine-based therapy (PAN-HEROIC-1): a phase 3 trial.

Cui Jiujie (2024) · Signal transduction and targeted therapy · n=298

Pulsed corneal crosslinking in the treatment of Keratoconus: a systematic review and meta-analysis.

Qureshi Maria (2025) · Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

Transarterial (chemo)embolisation versus systemic chemotherapy for colorectal cancer liver metastases.

Swierz Mateusz J (2024) · The Cochrane database of systematic reviews · n=118

Evaluation of CD3 and CD8 T-Cell Immunohistochemistry for Prognostication and Prediction of Benefit From Adjuvant Chemotherapy in Early-Stage Colorectal Cancer Within the QUASAR Trial.

Williams Christopher J M (2024) · Journal of clinical oncology : official journal of the American Society of Clinical Oncology · n=868

Total tumor volume predicts overall survival and response to induction chemotherapy in patients with colorectal cancer liver metastases: An ancillary study of the phase 3 CAIRO5 trial.

Michiel Zeeuw J (2025) · European journal of cancer (Oxford, England : 1990) · n=425

Nal-IRI/LV5-FU versus paclitaxel as second-line therapy in patients with metastatic esophageal squamous cell carcinoma (PRODIGE 62-FFCD 1701-OESIRI).

Tougeron David (2025) · European journal of cancer (Oxford, England : 1990)

Benefit of Chemoradiotherapy Versus Chemotherapy After Induction Therapy for Conversion of Unresectable Into Resectable Pancreatic Cancer: The Randomized CONKO-007 Trial.

Fietkau Rainer (2025) · Journal of clinical oncology : official journal of the American Society of Clinical Oncology · n=336

A140 plus mFOLFOX6 compared with cetuximab plus mFOLFOX6 for first-line RAS wild-type metastatic colorectal cancer: A randomized clinical trial.

Liu Rongrui (2025) · European journal of cancer (Oxford, England : 1990) · n=688

l-Carnitine and Alpha-Lipoic Acid Fail to Improve Anaerobic and Aerobic Performance in Trained Cyclists Despite a Reduction in Blood Lactate Concentration.

de Rozas Alejandro (2025) · Nutrients · n=19

Dapagliflozin combined with methylcobalamin in the treatment of type 2 diabetes mellitus with peripheral neuropathy: a systematic review and meta-analysis.

Deng Xiao-Long (2025) · Frontiers in endocrinology

Efficacy and safety of biweekly single-dose actinomycin D versus multiday methotrexate in low-risk gestational trophoblastic neoplasia: a prospective multicenter randomized trial.

Jiang F (2025) · Annals of oncology : official journal of the European Society for Medical Oncology · n=228

Perioperative Durvalumab in Gastric and Gastroesophageal Junction Cancer.

Janjigian Yelena Y (2025) · The New England journal of medicine · n=474

Acupoint injection increases the efficacy of vitamin B12 for diabetic neuropathy: a meta-analysis and trial sequential analysis.

Yu Yunfeng (2026) · European journal of clinical nutrition · n=1688

Nicorandil for prevention of contrast-induced nephropathy in patients undergoing coronary angiography: a meta-analysis.

Shaukat Ayesha (2025) · Future cardiology

A randomized, controlled trial to evaluate the efficacy of pyridoxine and ascorbic acid on cognitive function and quality of life in post-menopausal women.

Dhivya K (2025) · Naunyn-Schmiedeberg's archives of pharmacology

Appraising the causal relevance of maternal red blood cell folate and congenital heart disease in offspring: 2-sample Mendelian randomization.

Chen Hongyan (2025) · Annals of epidemiology

Nicotinic acid increases adipose tissue dietary fatty acid trapping and reduces postprandial hepatic and cardiac fatty acid uptake in prediabetes.

Montastier Émilie (2025) · European journal of pharmacology · n=19

Role of vitamins in the pathogenesis and treatment of restless leg syndrome: A systematic review and meta-analysis.

Xu Xiao-Min (2025) · PloS one

Vitamin B12, folate, and homocysteine levels in children and adolescents with obesity: a systematic review and meta-analysis.

Ulloque-Badaracco Juan R (2025) · Frontiers in public health · n=7791

Folic acid supplementation in children with sickle cell disease: a randomized double-blind noninferiority cross-over trial.

Williams Brock A (2025) · The American journal of clinical nutrition

Meta Analysis of Methylenetetrahydrofolate Reductase (MTHFR) C677T polymorphism and its association with folate and colorectal cancer.

Ye Meng (2025) · BMC cancer

Birth prevalence and determinants of neural tube defects among newborns in Ethiopia: A systematic review and meta-analysis.

Gebremariam Beminet Moges (2025) · PloS one

Investigational Use of Real-World Data as a Hybrid Control in Pancreatic Ductal Adenocarcinoma From the Randomized Phase Ib/II MORPHEUS Trial.

Ko Andrew H (2025) · Clinical pharmacology and therapeutics

Cognitive benefits of folic acid supplementation during pregnancy track with epigenetic changes at an imprint regulator.

Hilman L (2024) · BMC medicine

Safety and efficacy of adjuvant FOLFOX/FOLFIRI with versus without hepatic arterial infusion of floxuridine in patients following colorectal cancer liver metastasectomy (HARVEST trial): A randomized controlled trial.

Wang De-Shen (2025) · European journal of cancer (Oxford, England : 1990) · n=92

Biomechanical corneal effects of LASIK Xtra compared with conventional FS-LASIK in high myopic eyes.

Kaiser Klemens Paul (2025) · Journal of cataract and refractive surgery · n=19

First-Line Systemic Treatment for Initially Unresectable Colorectal Liver Metastases: Post Hoc Analysis of the CAIRO5 Randomized Clinical Trial.

Bond Marinde J G (2025) · JAMA oncology · n=530

Response of One-Carbon Biomarkers in Maternal and Cord Blood to Folic Acid Dose During Pregnancy.

Fleming Jennifer M (2024) · Nutrients

Hydroxocobalamin Versus Methylene Blue for Treatment of Vasoplegic Shock Following Cardiopulmonary Bypass: A Systematic Review and Meta-analysis.

Cadd Matthew (2024) · Journal of cardiothoracic and vascular anesthesia · n=263

A single-dose, randomized, crossover bioequivalence study of levamlodipine besilate tablets in healthy subjects.

Deng Qiaohuan (2025) · Naunyn-Schmiedeberg's archives of pharmacology

Homocysteine, vitamin B12, and folate circulating levels in women with and without polycystic ovary syndrome: A systematic review and meta-analysis.

Ulloque-Badaracco Juan R (2024) · Women's health (London, England)

mFOLFOX6 versus mFOLFOX6 + aflibercept as neoadjuvant treatment in MRI-defined T3-rectal cancer: a randomized phase-II-trial of the German Rectal Cancer Study Group (CAO/ARO/AIO 0214).

Hofheinz R-D (2024) · ESMO open · n=39

Steroids and Cross-Linking for Ulcer Treatment Trial II: Baseline Characteristics.

Prajna Venkatesh N (2024) · Cornea · n=132

Efficient topical treatments of cutaneous lupus erythematosus: a systematic review and network -meta-analysis.

Fukasawa Takemichi (2024) · Clinical and experimental dermatology · n=231

Cumulative incidence and risk of infection in patients with rheumatoid arthritis treated with janus kinase inhibitors: A systematic review and meta-analysis.

Ouranos Konstantinos (2024) · PloS one

Comparison of second-line chemotherapy regimens in advanced biliary tract cancer: a systematic review, meta-analysis, and population-based cohort study.

Leem Galam (2026) · International journal of surgery (London, England) · n=54

Prevalence and Risk Factors of Asthma in Children: A Systematic Review and Meta-analysis.

Yin Li (2025) · The Journal of asthma : official journal of the Association for the Care of Asthma · n=647414

Acupuncture for diabetic peripheral neuropathy: A systematic review and Bayesian network meta-analysis.

Lin Shuxiong (2025) · Medicine · n=5942

Spatial Tumor Immune Microenvironment as a Prognostic and Predictive Biomarker in Anti-EGFR-Based Maintenance for RAS wt Metastatic CRC-The PanaMa (AIO KRK0212) Trial.

Ballhausen Alexej (2025) · Clinical cancer research : an official journal of the American Association for Cancer Research · n=194

The Controversial Issue of Hypervitaminosis B12 as Prognostic Factor of Mortality: Global Lessons from a Systematic Review and Meta-Analysis.

Valdez-Martínez Edith (2025) · Nutrients · n=69610

Effects of quintuply-fortified salt on the micronutrient status of females of reproductive age in Punjab, India: a randomized, community-based trial.

Goh Yvonne E (2025) · The American journal of clinical nutrition

Efficacy of losartan plus modified FOLFIRINOX versus modified FOLFIRINOX in advanced pancreatic cancers: A randomized clinical trial (AFPAC Study).

Ramaswamy Anant (2025) · Cancer · n=88

Lenvatinib Plus Pembrolizumab and Chemotherapy Versus Chemotherapy in Advanced Metastatic Gastroesophageal Adenocarcinoma: The Phase III, Randomized LEAP-015 Study.

Shitara Kohei (2025) · Journal of clinical oncology : official journal of the American Society of Clinical Oncology · n=880

Associations of pretreatment emotional distress with adherence to therapy for patients with locally advanced rectal cancer: a post hoc analysis of the Chinese FOWARC phase 3 randomized clinical trial.

Shi Lishuo (2025) · BMC medicine · n=219

Proof of concept and design of an externally controlled trial for patients with gastro-enteropancreatic neuroendocrine carcinomas based on the randomized phase II BEVANEC trial.

Ganame S (2025) · European journal of cancer (Oxford, England : 1990) · n=2

Effect of Combined Vitamin C and Thiamine Therapy on Myocardial and Inflammatory Markers in Cardiac Surgery: A Randomized Controlled Clinical Trial.

Saetang Mantana (2025) · Nutrients · n=64

Molecular hyperselection for optimal choice of first-line targeted therapy independent of primary tumor sidedness: An exploratory analysis of the randomized FIRE-3 study performed in RAS wild-type metastatic colorectal cancer.

Weiss Lena (2025) · European journal of cancer (Oxford, England : 1990) · n=199

Liposomal irinotecan for previously treated patients with biliary tract cancer: A pooled analysis of NIFTY and NALIRICC trials.

Yoo Changhoon (2025) · Journal of hepatology · n=278

Evaluation of the Efficacy of a Serum Containing Niacinamide, Tranexamic Acid, Vitamin C, and Hydroxy Acid Compared to 4% Hydroquinone in the Management of Melasma.

Rocio Juliane (2025) · Journal of cosmetic dermatology

Effect of adjuvant chemotherapy with toad venom injection in the treatment of intermediate and advanced colon cancer and its effect on cellular immunity, PTEN, and PI3k.

Ding Haijun (2025) · Anti-cancer drugs · n=148

Efficacy analysis of folic acid in chronic atrophic gastritis with Helicobacter pylori infection: a systematic review and meta-analysis.

Li Hui (2025) · BMC gastroenterology · n=1364

Encorafenib, cetuximab and chemotherapy in BRAF-mutant colorectal cancer: a randomized phase 3 trial.

Kopetz Scott (2025) · Nature medicine

[The effectiveness of Cytoflavin in the medical rehabilitation of elderly and senile patients].

Bolotova E V (2024) · Terapevticheskii arkhiv · n=66

Comparative efficacy and safety of metformin, anti-obesity agents, and myoinositol in improving IVF/ICSI outcomes and reducing ovarian hyperstimulation syndrome in women with polycystic ovary syndrome: a systematic review and network meta-analysis.

Lin Lijun (2024) · Journal of ovarian research · n=1827

Effect of Early-Life Lipid-Based Nutrient Supplement and Home Environment on Autonomic Nervous System Regulation at 9-11 Years: A Follow-Up of a Randomized Controlled Trial.

Aryee Lois M D (2025) · Maternal & child nutrition

Pancreatic Adenocarcinoma: Long-Term Outcomes of Adjuvant Therapy in the ESPAC4 Phase III Trial.

Palmer Daniel H (2025) · Journal of clinical oncology : official journal of the American Society of Clinical Oncology · n=4

Clinical and Dermoscopic Comparison of the Efficacy and Safety of 5% Fluorouracil Topical Cream and 1% Niacinamide Topical Gel in the Treatment of Actinic Keratosis: A Randomized Controlled Trial.

Poostiyan Nazila (2025) · Journal of cosmetic dermatology · n=26

Prognostic factors in localized pancreatic ductal adenocarcinoma after neoadjuvant therapy and resection: a systematic review and meta-analysis.

Javed Ammar A (2025) · Journal of the National Cancer Institute · n=92

Systematic Review and Meta-Analysis on the Association Between Daily Niacin Intake and Glaucoma.

Nicola Constantin Alin (2024) · Nutrients

Second-Line Fluoropyrimidine-Based Chemotherapy in Advanced Biliary Tract Cancer: A Meta-analysis Based on Individual Patient-Level Data of Randomized Trials.

Hyung Jaewon (2025) · Cancer research and treatment · n=88

A systematic review and meta-analysis of functional vitamin B12 status among adult vegans.

Niklewicz Ali (2024) · Nutrition bulletin

Folate intake and the risk of endometrial cancer: A dose-response meta-analysis.

Long Jiaye (2024) · Medicine · n=379570

Efficacy of oral folinic acid supplementation in children with autism spectrum disorder: a randomized double-blind, placebo-controlled trial.

Panda Prateek Kumar (2024) · European journal of pediatrics · n=40

Oxaliplatin Added to Fluoropyrimidine/Bevacizumab as Initial Therapy for Unresectable Metastatic Colorectal Cancer in Older Patients: A Multicenter, Randomized, Open-Label Phase III Trial (JCOG1018).

Takashima Atsuo (2024) · Journal of clinical oncology : official journal of the American Society of Clinical Oncology · n=125

Influence of myo-inositol on metabolic status for gestational diabetes: a meta-analysis of randomized controlled trials.

Chen Huan (2024) · The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · n=317

Vitamin Profile of the Patients with Chronic Kidney Disease Receiving a Novel Total Parenteral Nutrition Formula: Multicenter Randomized Controlled Phase III Trial.

Tsuchiya Ken (2026) · Annals of nutrition & metabolism · n=63

A Systematic Review and Meta-Analysis Comparing Epithelium-On and Epithelium-Off Corneal Collagen Cross-Linking in Keratoconus Management: Integrating New Evidence.

Mohammadpour Mehrdad (2025) · Cornea

The Fertility Effects of the C677T Mutation in the Methylenetetrahydrofolate Reductase Gene: A Cross-Site Systematic Review and Meta-Analysis.

MacLean Caroline A (2025) · American journal of human biology : the official journal of the Human Biology Council

Modified Fluorouracil, Leucovorin, Irinotecan, and Oxaliplatin or S-1, Irinotecan, and Oxaliplatin Versus Nab-Paclitaxel + Gemcitabine in Metastatic or Recurrent Pancreatic Cancer (GENERATE, JCOG1611): A Randomized, Open-Label, Phase II/III Trial.

Ohba Akihiro (2025) · Journal of clinical oncology : official journal of the American Society of Clinical Oncology · n=527

Micronutrient supplementation influences the composition and diet-originating function of the gut microbiome in healthy adults.

Mckirdy Shona (2025) · Clinical nutrition (Edinburgh, Scotland)

Infant vitamin B12 status and its predictors - cross-sectional baseline results from an ongoing randomized controlled trial.

Bjørkevoll Sol Maja G (2025) · The American journal of clinical nutrition · n=644

Impact of Lean Body Mass-Based Oxaliplatin Dose Calculation on Neurotoxicity in Adjuvant Treatment of Stage III Colon Cancer: Results of the Phase II Randomized LEANOX Trial.

Assenat Eric (2025) · Journal of clinical oncology : official journal of the American Society of Clinical Oncology · n=63

Encorafenib, Cetuximab, and mFOLFOX6 in BRAF-Mutated Colorectal Cancer.

Elez Elena (2025) · The New England journal of medicine

PRODIGE 29-UCGI 26 (NEOPAN): A Phase III Randomized Trial Comparing Chemotherapy With FOLFIRINOX or Gemcitabine in Locally Advanced Pancreatic Carcinoma.

Ducreux Michel (2025) · Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Assessing the adherence and acceptability to iron and folic acid compared with multiple micronutrient supplements during pregnancy: a cluster-randomized noninferiority trial in Cambodia.

Sauer Cassandra (2025) · The American journal of clinical nutrition · n=515

TFOX versus FOLFOX in first-line treatment of patients with advanced HER2-negative gastric or gastro-oesophageal junction adenocarcinoma (PRODIGE 51- FFCD-GASTFOX): an open-label, multicentre, randomised, phase 3 trial.

Zaanan Aziz (2025) · The Lancet. Oncology · n=507

Meta-analysis of niacin and NAD metabolite treatment in infectious disease animal studies suggests benefit but requires confirmation in clinically relevant models.

Curran Colleen S (2025) · Scientific reports

Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis.

Tavares Rodrigues Luiz Phelipe (2025) · Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia · n=11377

Use of Hydroxycobolamin in the Prevention of Vasoplegic Syndrome in Adult Patients Undergoing Cardiopulmonary Bypass: A Controlled Prospective Trial.

Salah Dina (2025) · Journal of cardiothoracic and vascular anesthesia · n=30

Effect of Nutritional Supplements for Reducing Homocysteine Levels in Healthy Adults: A Systematic Review and Network Meta-Analysis of Randomized Trials.

Liu Cai (2025) · Nutrition reviews

Single-dose intravenous iron vs oral iron for treatment of maternal iron deficiency anemia: a randomized clinical trial.

Derman Richard J (2025) · American journal of obstetrics and gynecology · n=1462

Comparative efficacy of combined myo-inositol and D-chiro inositol versus metformin across PCOS Phenotypes: enhancing ovarian function, ovulation, and stress response in a prospective clinical trial.

Gul Meena (2025) · Naunyn-Schmiedeberg's archives of pharmacology · n=60

Pyridoxine Prevents Postoperative Nausea and Vomiting in Gynecologic Laparoscopic Surgery: A Double-blind Randomized Controlled Trial.

Zhang Qirui (2025) · Anesthesiology · n=442

Language processing in breastfed infants at risk of thiamine deficiency benefits from maternal thiamine supplementation.

Baldwin Dare A (2025) · Developmental psychology

Phase 2A Proof-of-Concept Double-Blind, Randomized, Placebo-Controlled Trial of Nicotinamide in Early Alzheimer Disease.

Grill Joshua D (2025) · Neurology · n=47

Chemotherapy and radiotherapy for advanced pancreatic cancer.

Haggstrom Lucy (2024) · The Cochrane database of systematic reviews · n=11333

Modified FOLFOXIRI plus cetuximab versus bevacizumab in RAS wild-type metastatic colorectal cancer: a randomized phase II DEEPER trial.

Shiozawa Manabu (2024) · Nature communications · n=359

Absorption, anti-inflammatory, antioxidant, and cardioprotective impacts of a novel fasting mimetic containing spermidine, nicotinamide, palmitoylethanolamide, and oleoylethanolamide: A pilot dose-escalation study in healthy young adult men.

Rhodes Christopher H (2024) · Nutrition research (New York, N.Y.)

Effects of dexamethasone combined with vitamin B12 on percutaneous endoscopic interlaminar discectomy early outcomes: a randomized controlled trial.

He Cheng (2024) · Journal of orthopaedic surgery and research

The phageome of patients with ulcerative colitis treated with donor fecal microbiota reveals markers associated with disease remission.

Majzoub Marwan E (2024) · Nature communications

Burden of neural tube defects in India: a systematic review and meta-analysis.

Sinha Anuvi (2024) · Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials.

Nakanishi Nobuto (2024) · Clinical nutrition (Edinburgh, Scotland) · n=3494

Dose Justification for Asciminib in Patients with Philadelphia Chromosome-Positive Chronic Myeloid Leukemia with and Without the T315I Mutation.

Combes Francois Pierre (2024) · Clinical pharmacokinetics · n=199

High-dose Vitamin-B6 reduces sensory over-responsivity.

Cracknell Rebekah O (2024) · Journal of psychopharmacology (Oxford, England) · n=300

Assessing a Fermented Whey Beverage Biofortified with Folate as a Potential Folate Source for Humans.

Obermaier Lisa (2024) · Molecular nutrition & food research

The effectiveness of vitamin B6 in reducing mastalgia: a systematic review and meta-analysis.

Sharifipour Foruzan (2025) · BMC women's health · n=951

Pembrolizumab Plus Chemotherapy Versus Chemotherapy as Perioperative Therapy in Locally Advanced Gastric and Gastroesophageal Junction Cancer: Final Analysis of the Randomized, Phase III KEYNOTE-585 Study.

Shitara Kohei (2025) · Journal of clinical oncology : official journal of the American Society of Clinical Oncology · n=804

Chicken liver and eggshell crackers are a safe and affordable animal source food for overcoming micronutrient deficits during pregnancy and lactation in Indonesia: a double-blind, cluster randomized controlled trial (SISTIK Growth Study).

Diana Aly (2025) · BMC pregnancy and childbirth

Addressing Anemia Among Adolescents in Zanzibar With School-based Supplementation of Once Weekly Iron-folic Acid or Daily Multiple Micronutrients: A Cluster-randomized Trial.

Cliffer Ilana R (2025) · The Journal of adolescent health : official publication of the Society for Adolescent Medicine

Recurrence Patterns of Esophageal Adenocarcinoma in the Phase III ESOPEC Trial Comparing Perioperative Chemotherapy With Preoperative Chemoradiotherapy.

Hoeppner Jens (2025) · Journal of clinical oncology : official journal of the American Society of Clinical Oncology · n=438

Corneal biomechanical property changes following corneal collagen cross-linking in keratoconus: a systematic review and meta-regression analysis.

Krungkraipetch Luksanaporn (2025) · International ophthalmology

Impact of Vitamin B1 and Vitamin B2 Supplementation on Anxiety, Stress, and Sleep Quality: A Randomized, Double-Blind, Placebo-Controlled Trial.

Tao Yingxuan (2025) · Nutrients · n=43

Interventional arterial chemotherapy versus sorafenib for advanced hepatocellular carcinoma in China: a health economic evaluation of open-label, randomised, phase 3 study.

Chen Qi-Feng (2025) · BMJ open

Safety and Efficacy of High-Dose Folinic Acid in Children with Autism: The Impact of Folate Metabolism Gene Polymorphisms.

Zhang Caiyun (2025) · Nutrients · n=50

Asciminib remained superior vs bosutinib in late-line CML-CP after nearly 4 years of follow-up in ASCEMBL.

Mauro Michael J (2025) · Blood advances · n=25

The Effect of Nicotinamide Mononucleotide and Riboside on Skeletal Muscle Mass and Function: A Systematic Review and Meta-Analysis.

Prokopidis Konstantinos (2025) · Journal of cachexia, sarcopenia and muscle

Short-Term Effects of Folate Supplementation in Combination With Vitamin B6 for Treating Acute Manic Episodes in Bipolar I Disorder: A Randomized Controlled Trial.

Akbarzadeh Farzad (2025) · Brain and behavior · n=43

Effects of Nicorandil, Isosorbide Mononitrate, or Diltiazem on Radial Artery Grafts After CABG: The Randomized ASRAB-Pilot Trial.

Zhu Yunpeng (2025) · Circulation. Cardiovascular interventions · n=50

Meta-analysis to determine the effects of supplementation of niacin during the transition or lactation period on performance in dairy cows.

Arshad U (2025) · Journal of dairy science · n=13

Micronutrient deficiencies in patients with celiac disease: A systematic review and meta-analysis.

Lamjadli Saad (2025) · International journal of immunopathology and pharmacology

Liver metastases do not predict resistance to the addition of atezolizumab to first-line FOLFOXIRI plus bevacizumab in proficient MMR metastatic colorectal cancer: a secondary analysis of the AtezoTRIBE study.

Antoniotti C (2025) · ESMO open

Perioperative Chemotherapy or Preoperative Chemoradiotherapy in Esophageal Cancer.

Hoeppner Jens (2025) · The New England journal of medicine · n=221

Improvement in biochemical manifestations of the serum and follicular fluid and ICSI outcomes in PCOS patients with myo-inositol administration: prospective randomized research.

Yazdanpanah Zeynab (2025) · Naunyn-Schmiedeberg's archives of pharmacology

Effects of different supplements on Hashimoto's thyroiditis: a systematic review and network meta-analysis.

Peng Bingcong (2024) · Frontiers in endocrinology

Neoadjuvant Modified Infusional Fluorouracil, Leucovorin, and Oxaliplatin With or Without Radiation Versus Fluorouracil Plus Radiation for Locally Advanced Rectal Cancer: Updated Results of the FOWARC Study After a Median Follow-Up of 10 Years.

Zhang Jianwei (2025) · Journal of clinical oncology : official journal of the American Society of Clinical Oncology · n=495

Efficacy and Safety of KH903 Plus FOLFIRI as a Second-Line Treatment in Unresectable Recurrent or Metastatic Colorectal Cancer: A Randomized Phase 2 Study.

Li Jian (2025) · Clinical colorectal cancer · n=122

Trilaciclib prior to FOLFOXIRI/bevacizumab for patients with untreated metastatic colorectal cancer: phase 3 PRESERVE 1 trial.

Lenz Heinz-Josef (2025) · JNCI cancer spectrum

Effect of nicotinamide riboside on airway inflammation in COPD: a randomized, placebo-controlled trial.

Norheim Kristoffer L (2024) · Nature aging

Comparative efficacy and safety of Chinese patent medicines as an adjunctive therapy for diabetic peripheral neuropathy: systematic review and network meta-analysis of randomized controlled trials.

Wang Qun (2024) · Pharmaceutical biology

Morphomics, Survival, and Metabolites in Patients With Metastatic Pancreatic Cancer.

Gunchick Valerie (2024) · JAMA network open · n=528

Effect of roasted purple laver (nori) on vitamin B12 nutritional status of vegetarians: a dose-response trial.

Huang Qian-Ni (2024) · European journal of nutrition

Causal relationship between folic acid and prostate cancer risk: Insights from Mendelian randomization analysis.

Guo Xiaoxiao (2024) · International journal of urology : official journal of the Japanese Urological Association

Relationships of B12 and Homocysteine with Outcomes in the SURE-PD, SURE-PD3, and STEADY-PDIII Trials.

Christine Chadwick W (2024) · Journal of Parkinson's disease

Topical Formulation with Niacinamide Combined with 5 MHz Ultrasound for Improving Skin Ageing: A Double-blind, Randomised, Placebo-controlled Clinical Study.

Vergilio Mariane Massufero (2025) · Current medicinal chemistry

Comparative Evaluation of Anterior Segment Optical Coherence Tomography Findings Following Accelerated Corneal Crosslinking Protocols Using Different Riboflavin Formulations and Soaking Durations.

Celik-Buyuktepe Tuna (2025) · Current eye research · n=26

Short-course-based TNT with or without PD-1 inhibitor for pMMR locally advanced rectal cancer: Phase 2 results of a randomized trial (STELLAR II).

Tang Yuan (2025) · Med (New York, N.Y.) · n=110

Electroacupuncture frequency for chemotherapy-induced neuropathy in breast cancer: a randomized controlled trial.

Shen Qiongying (2025) · The oncologist

Health-related quality of life and performance status with NALIRIFOX versus nab-paclitaxel + gemcitabine in treatment-naive patients with metastatic pancreatic ductal adenocarcinoma: results from the NAPOLI 3 trial.

Melisi D (2025) · ESMO open · n=383

Role of B vitamins in modulating homocysteine and metabolic pathways linked to brain atrophy: Metabolomics insights from the VITACOG trial.

Kacerova Tereza (2025) · Alzheimer's & dementia : the journal of the Alzheimer's Association

A randomised controlled trial on cross-linking protocols for the treatment of progressive keratoconus using isoosmolar and hypoosmolar riboflavin with the addition of sterile water in thin corneae.

Gustafsson Ingemar (2026) · Acta ophthalmologica

Beyond Folate: The Emerging Role of Maternal Vitamin B12 in Neural Tube Development.

Nie Lirong (2025) · Nutrients

Effectiveness of Nicorandil in Heart Failure: A Meta-Analysis.

Mu Tongge (2025) · Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

Improving HbA1c Levels by Methylcobalamin Vitamin in Diabetic Volunteers, Combined with Dapagliflozin as Type 2 Diabetes Mellitus Routine Treatment: A Controlled Randomized, Double-blind Trial.

Aburayyan Walid (2025) · Iranian journal of medical sciences · n=160

Modifiable Nutritional Biomarkers in Autism Spectrum Disorder: A Systematic Review and Meta-Analysis of Vitamin D, B12, and Homocysteine Exposure Spanning Prenatal Development Through Late Adolescence.

Avram Oana-Elisabeta (2025) · International journal of molecular sciences · n=11

First-line treatment of anti-EGFR monoclonal antibody cetuximab β plus FOLFIRI versus FOLFIRI alone in Chinese patients with RAS/BRAF wild-type metastatic colorectal cancer: a randomized, phase 3 trial.

Shi Yuankai (2025) · Signal transduction and targeted therapy

Safety, Tolerability, and Pharmacokinetics of the Neuroprotectant 2-Iminobiotin in Patients With Large-Vessel Occlusion Ischemic Stroke Treated With Endovascular Thrombectomy.

Vos Erik M (2025) · Stroke · n=40

Effect of myo-inositol supplementation in mixed ovarian response IVF cohort: a systematic review and meta-analysis.

Zhang Jianeng (2025) · Frontiers in endocrinology · n=981

Short-Term Dietary Caffeine Intake for Alleviating Symptoms of Burning Mouth Syndrome: A Randomised Controlled Comparison With Alpha-Lipoic Acid.

Wu Chuanji (2025) · Journal of oral rehabilitation

Effectiveness of acupoint injection combined with specific electromagnetic spectrum irradiation and acupuncture on peripheral facial paralysis.

Sun Meihua (2025) · Neurological research · n=85

Causal relationship between B vitamins and neuropsychiatric disorders: A systematic review and meta-analysis.

Ye Mengfei (2025) · Neuroscience and biobehavioral reviews

Baseline Liquid Biopsy in Relation to Tissue-Based Parameters in Metastatic Colorectal Cancer: Results From the Randomized FIRE-4 (AIO-KRK-0114) Study.

Stintzing Sebastian (2025) · Journal of clinical oncology : official journal of the American Society of Clinical Oncology · n=540

Posttreatment Blood Pressure as a Key Predictor in a 5-Year Stroke Prediction Model.

Zhang Nan (2025) · Journal of clinical hypertension (Greenwich, Conn.)

Effectiveness of Health Education Interventions in Enhancing Iron-Folic Acid Supplement Utilization Among Pregnant Women: Systematic Review and Meta-analysis.

Feyisa Jira Wakoya (2025) · Nutrition reviews

Asciminib add-on to imatinib demonstrates sustained high rates of ongoing therapy and deep molecular responses with prolonged follow-up in the ASC4MORE study.

Hughes Timothy P (2024) · Journal of hematology & oncology · n=84

Prognostic value of radiologic and pathological response in colorectal cancer liver metastases upon systemic induction treatment: subgroup analysis of the CAIRO5 trial.

Bond M J G (2024) · ESMO open · n=242

Maintenance with 5-FU/LV-aflibercept after induction with FOLFIRI-aflibercept versus FOLFIRI-aflibercept until progression as second-line treatment in older adults with metastatic colorectal cancer: the AFEMA phase II randomized trial.

García-Alfonso P (2024) · ESMO open · n=35

Intermittent or Continuous Panitumumab Plus Fluorouracil, Leucovorin, and Irinotecan for First-Line Treatment of RAS and BRAF Wild-Type Metastatic Colorectal Cancer: The IMPROVE Trial.

Avallone Antonio (2025) · Journal of clinical oncology : official journal of the American Society of Clinical Oncology · n=65

Comparison of first-line chemotherapy regimens in unresectable locally advanced or metastatic pancreatic cancer: a systematic review and Bayesian network meta-analysis.

Mastrantoni Luca (2024) · The Lancet. Oncology · n=168

A Randomized Crossover Trial of Acceptability of Quadruple-Fortified Salt in Women and their Households in Southern India.

Guetterman Heather M (2025) · The Journal of nutrition · n=77

Chemotherapy switch for localized pancreatic cancer: a systematic review and meta-analysis.

Dekker Esther N (2024) · The British journal of surgery · n=863

Effect analysis of tanshinone IIA sulfonate sodium combined with a-lipoic acid in patients with diabetes peripheral neuropathy.

Cheng Mingyu (2024) · Pakistan journal of pharmaceutical sciences · n=52

Induction treatment with FOLFIRINOX or oxaliplatin-based doublet followed by long-course chemoradiotherapy and surgery in locally advanced rectal cancer. A systematic review and pooled analysis from phase II and III trials.

Moretto Roberto (2024) · Cancer treatment reviews · n=674

Clinico-biological factors predicting the benefit of the LV5FU2 maintenance strategy as a first-line therapy in patients with metastatic pancreatic cancer.

Boisteau Emeric (2024) · The oncologist

Effect of dietary myo-inositol supplementation on the insulin resistance and the prevention of gestational diabetes mellitus: an open-label, randomized controlled trial.

Asimakopoulos George (2024) · Archives of gynecology and obstetrics

Devimistat (CPI-613) With Modified Fluorouarcil, Oxaliplatin, Irinotecan, and Leucovorin (FFX) Versus FFX for Patients With Metastatic Adenocarcinoma of the Pancreas: The Phase III AVENGER 500 Study.

Philip Philip A (2024) · Journal of clinical oncology : official journal of the American Society of Clinical Oncology

The effect of fruit smoothie supplementation on psychological distress and biomarkers among people with opioid dependence receiving opioid agonist therapy: a randomized controlled trial.

Javadi Arjmand Elaheh (2025) · BMC medicine · n=311

The potential adding therapeutic effect of pentoxifylline and/or folic acid for chronic kidney disease patients: randomized controlled trial.

Galal Amira Reda Muhammad (2025) · BMC nephrology · n=80

Dietary and Circulating Vitamins, Polymorphisms of Vitamin Metabolism Genes, and the Risk of Gastrointestinal Cancers: A Systematic Review and Meta-Analysis.

Wang Xin-Ling (2025) · Clinical and translational gastroenterology

Effect of 40:1 myo-inositol/D-chiro-inositol treatment on serum asprosin levels in polycystic ovary syndrome: a prospective randomized pilot study.

Ozay Ozlen Emekci (2025) · Ginekologia polska · n=30

Nodal Downstaging in Patients With Rectal Cancer: Survival Is Promising if YpN0 Is Achieved.

Wan Haigui (2025) · Diseases of the colon and rectum · n=449

Final Results of ERBIMOX: A Randomized Phase II Study of Modified FOLFOX7 With or Without Cetuximab as First-Line Treatment for KRAS Wild-type Metastatic Colorectal Cancer.

Potthoff Karin (2025) · Journal of gastrointestinal cancer · n=138

Nicotinamide Riboside Supplementation Benefits in Patients With Werner Syndrome: A Double-Blind Randomized Crossover Placebo-Controlled Trial.

Shoji Mayumi (2025) · Aging cell

Neurometabolite Alterations Associated With Cannabis Use: A Proton Magnetic Resonance Spectroscopy Meta-Analysis.

Kirkland Anna E (2025) · Human brain mapping

Nicotinamide modulates gut microbial metabolic potential and accelerates recovery in mild-to-moderate COVID-19.

Schreiber Stefan (2025) · Nature metabolism

Efficacy of Alpha Lipoic Acid Supplementation in Sperm Parameters: A Systematic Review and Meta-Analysis of Randomized Trials.

Pires Iago Zang (2025) · International braz j urol : official journal of the Brazilian Society of Urology · n=250

Vitamin B6 status is related to disease severity and modulated by endurance exercise in individuals with multiple sclerosis: a secondary analysis of a randomized controlled trial.

Belen Sergen (2025) · The American journal of clinical nutrition · n=47

FOLFIRI with cetuximab or bevacizumab in RAS wild-type metastatic colorectal cancer: Refining first-line treatment selection by combining clinical parameters: A post hoc analysis of the randomized open-label phase III trial FIRE-3/AIO KRK0306.

Holch Julian Walter (2025) · European journal of cancer (Oxford, England : 1990)

Evaluating the Effect of Epigallocatechin Gallate (EGCG) in Reducing Folate Levels in Reproductive Aged Women by MTHFR and DHFR Genotype in Combination With Letrozole or Clomiphene.

Johnson Jeremy J (2025) · Clinical and translational science · n=39

Effects of lipid-based nutrient supplements on gut markers in stunted children: Secondary analysis of a randomised trial.

Pesu Hannah (2025) · Journal of pediatric gastroenterology and nutrition

Efficacy and safety of nicorandil for prevention of contrast-induced nephropathy in patients undergoing coronary procedures: a systematic review and meta-analysis.

Butt Ayesha Imran (2025) · International urology and nephrology · n=2787

A Randomized Controlled Study on the Clinical Efficacy of Ginkgo Biloba Combined with Nicorandil in Patients with HFmrEF.

Gao Xiang (2025) · International heart journal · n=316

Effect of Dendrobium Officinale on Radioactive Oral Mucositis of Nasopharyngeal Carcinoma and Changes of Oral Microecology.

Yang Jiaying (2025) · Integrative cancer therapies

Second-line systemic treatment for metastatic colorectal cancer: A systematic review and Bayesian network meta-analysis based on RCT.

Sun Chengyu (2024) · PloS one · n=16925

Evaluation of the Efficacy of the Addition of a Combination of Pyrimidine Nucleotides and Vitamin B1 and B12 to Standard Treatment in the Management of Painful Radiculopathy and in the Quality of Life of Patients.

Monfort Jordi (2024) · Nutrients · n=122

Is there a causal link between folate status and schizophrenia? Evidence from genetic association studies.

Yoo Samantha (2025) · Nutritional neuroscience

Association of dietary patterns derived by reduced-rank regression with colorectal cancer risk and mortality.

Abebe Zegeye (2024) · European journal of nutrition

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Kotov S V (2024) · Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova · n=21

Accelerated versus conventional corneal collagen cross-linking for keratoconus: A meta-analysis of randomized controlled trials.

Yeh Cyuan Yi (2025) · European journal of ophthalmology

Serum Concentrations of Folate Forms Following Supplementation of Multimicronutrients with 400 µg or 800 µg Mix of (6S)-5-Methyltetrahydrofolate and Folic Acid (1:1) in Women of Childbearing Age.

Obeid Rima (2024) · Molecular nutrition & food research

Feasibility of telehealth exercise and nicotinamide riboside supplementation in survivors of childhood cancer at risk for diabetes: A pilot randomized controlled trial.

Bhandari Rusha (2025) · Pediatric blood & cancer · n=20

Comparison of metformin with inositol versus metformin alone in women with polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials.

Kelly Francinny Alves (2025) · Endocrine · n=388

Effects of Mecobalamin on the Functional Outcomes of Complex Regional Pain Syndrome Type 1 of the Foot and Ankle.

Arunakul Marut (2024) · Foot & ankle international · n=23

Association between folate level and cervical intraepithelial neoplasia risk: a systematic review and meta-analysis.

Chen Run (2025) · European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP)

Vitamin B12 Status in Vegan and Vegetarian Seventh-Day Adventists: A Systematic Review and Meta-Analysis of Serum Levels and Dietary Intake.

Janko Robert K (2025) · American journal of health promotion : AJHP · n=1994

Effectiveness of Myo-Inositol on Oocyte and Embryo Quality in Assisted Reproduction: Systematic Review and Meta-Analysis of Randomized Clinical Trials.

Pivazyan Laura (2025) · Gynecologic and obstetric investigation · n=820

Preconception Folic Acid and Multivitamin Supplementation for the Prevention of Neural Tube Defect: An Umbrella Review of Systematic Review and Meta-analysis.

Abate Biruk Beletew (2025) · Neuroepidemiology · n=10

Is There any Benefit of Addition of Neo-Adjuvant Chemotherapy (FOLFOX4) to Standard Preoperative Treatment of Rectal Cancer? A Randomized Clinical Trial.

Mosallum Hanan Selim (2024) · Asian Pacific journal of cancer prevention : APJCP · n=67

Docetaxel-oxaliplatin-capecitabine/5-fluorouracil (DOX/F) followed by docetaxel versus oxaliplatin-capecitabine/5-fluorouracil (CAPOX/FOLFOX) in HER2-negative advanced gastric cancers.

Ramaswamy Anant (2024) · JNCI cancer spectrum · n=324

Hydrogen-Rich Gas Enhanced Sprint-Interval Performance: Metabolomic Insights into Underlying Mechanisms.

Dong Gengxin (2024) · Nutrients

Daily Vinegar Ingestion Improves Depression and Enhances Niacin Metabolism in Overweight Adults: A Randomized Controlled Trial.

Barrong Haley (2024) · Nutrients

A Comparative Study Evaluating the Effectiveness of Folate-Based B Vitamin Intervention on Cognitive Function of Older Adults under Mandatory Folic Acid Fortification Policy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Zhang Liyang (2024) · Nutrients · n=42768

Alliance A022104/NRG-GI010: The Janus Rectal Cancer Trial: a randomized phase II/III trial testing the efficacy of triplet versus doublet chemotherapy regarding clinical complete response and disease-free survival in patients with locally advanced rectal cancer.

Alvarez Janet A (2024) · BMC cancer · n=760

Early tumor shrinkage as a prognostic predictor in chemotherapy-naïve patients with locally advanced pancreatic cancer treated with modified FOLFIRINOX or gemcitabine plus nab-paclitaxel combination therapy: An exploratory analysis of JCOG1407.

Tezuka Shun (2024) · Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] · n=126

Safety of first-line systemic therapy in patients with metastatic colorectal cancer: a network meta-analysis of randomized controlled trials.

Zhan Yanrong (2024) · BMC cancer · n=17351

COLUMBIA-1: a randomised study of durvalumab plus oleclumab in combination with chemotherapy and bevacizumab in metastatic microsatellite-stable colorectal cancer.

Segal Neil H (2024) · British journal of cancer

Can proximal gastrectomy with double-tract reconstruction replace total gastrectomy? a meta-analysis of randomized controlled trials and propensity score-matched studies.

Zhu Guangxu (2024) · BMC gastroenterology · n=1154

Ticagrelor modestly raises plasma riboflavin concentration in humans and inhibits riboflavin transport by BCRP and MRP4.

Deng Feng (2024) · Clinical pharmacology and therapeutics

Combination of neoadjuvant and adjuvant chemotherapy with FOLFOX compared with adjuvant chemotherapy in management of locally advanced rectal cancers: a randomized trial of a promising therapeutic approach.

Biniaz Mandana (2024) · BMC cancer · n=286

Postoperative Adverse Events Following Neoadjuvant Therapy and Surgery for Borderline Resectable Pancreatic Cancer in a Phase 2 Clinical Trial (Alliance A021501).

Snyder Rebecca A (2024) · Annals of surgical oncology · n=32

Skeletal muscle quality predicts overall survival in advanced liver hepatocellular carcinoma treated with SIRT and sorafenib: A subanalysis of the SORAMIC trial.

Surov Alexey (2024) · United European gastroenterology journal · n=363

A randomized phase II trial of Captem or Folfiri as second-line therapy in neuroendocrine carcinomas.

Bongiovanni Alberto (2024) · European journal of cancer (Oxford, England : 1990) · n=25

Dermatology-related quality-of-life outcomes in patients with RAS wild-type metastatic colorectal cancer treated with fluorouracil and folinic acid with or without panitumumab (Pmab) maintenance after FOLFOX + Pmab induction: a prespecified secondary analysis of the phase II randomized PanaMa (AIO KRK 0212) trial.

Ballhausen A (2024) · ESMO open · n=387

Total neoadjuvant therapy with mFOLFIRINOX versus preoperative chemoradiotherapy in patients with locally advanced rectal cancer: long-term results of the UNICANCER-PRODIGE 23 trial.

Conroy T (2024) · Annals of oncology : official journal of the European Society for Medical Oncology

Clinical outcomes of liposomal irinotecan in patients with advanced pancreatic cancer previously treated with conventional irinotecan: A meta-analysis of real-world evidence.

Gupta Amol (2024) · Cancer · n=1368

Effectiveness of dual combination therapy of acarbose plus metformin and acarbose plus myo-inositol in ameliorating the metabolic and endocrinologic complications of polycystic ovary syndrome - A randomized controlled trial.

Andavar Marina (2024) · European journal of obstetrics, gynecology, and reproductive biology

Early findings in a randomised controlled trial on crosslinking protocols using isoosmolar and hypoosmolar riboflavin for the treatment of progressive keratoconus.

Gustafsson Ingemar (2025) · Acta ophthalmologica

Effects of folic acid supplementation on cognitive function and inflammation in elderly patients with mild cognitive impairment: A systematic review and meta-analysis of randomized controlled trials.

Wang Mingchen (2024) · Archives of gerontology and geriatrics · n=1102

The role of nutraceuticals in the management of temporomandibular disorders.

Di Giacomo Paola (2024) · Journal of complementary & integrative medicine · n=40

B vitamins and bone health: a meta-analysis with trial sequential analysis of randomized controlled trials.

Luo Yan (2024) · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · n=34700

Sequential therapy of refractory metastatic pancreatic cancer with 5-FU/LV/irinotecan (FOLFIRI) vs. 5-FU/LV/oxaliplatin (OFF). The PANTHEON trial (AIO PAK 0116).

Modest Dominik Paul (2024) · Journal of cancer research and clinical oncology

Folate Biomarkers, Folate Intake, and Risk of Death From All Causes, Cardiovascular Disease, and Cancer: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies.

Fallah Melika (2025) · Nutrition reviews · n=304

Role of Thiamine Supplementation in the Treatment of Chronic Heart Failure: An Updated Meta-Analysis of Randomized Controlled Trials.

He Shuai (2024) · Clinical cardiology · n=274

Effect of maternal postnatal balanced energy protein supplementation and infant azithromycin on infant growth outcomes: an open-label randomized controlled trial.

Muhammad Ameer (2024) · The American journal of clinical nutrition

Neurochemical changes in the progression of Huntington's disease: A meta-analysis of in vivo1H-MRS studies.

Jing Yinghua (2024) · Neurobiology of disease · n=306

Assessment of the Predictive Ability of Theranostics for Corneal Cross-linking in Treating Keratoconus: A Randomized Clinical Trial.

Roszkowska Anna Maria (2024) · Ophthalmology

The efficacy and safety of different Janus kinase inhibitors as monotherapy in rheumatoid arthritis: A Bayesian network meta-analysis.

Qu Bingjia (2024) · PloS one · n=15961

Vitamins B9 and B12 in children with attention deficit hyperactivity disorder (ADHD).

Razavinia Fatemeh (2024) · International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition

Clinical Evaluation of Effectiveness and Safety of Combined Use of Dietary Supplements Amberen® and Smart B® in Women with Climacteric Syndrome in Perimenopause.

Kachko Vera A (2024) · Advances in therapy · n=106

QUATTRO-II randomized trial: CAPOXIRI+bevacizumab vs. FOLFOXIRI+bevacizumab as first-line treatment in patients with mCRC.

Bando Hideaki (2024) · Med (New York, N.Y.) · n=52

Effect of Methylfolate, Pyridoxal-5'-Phosphate, and Methylcobalamin (SolowaysTM) Supplementation on Homocysteine and Low-Density Lipoprotein Cholesterol Levels in Patients with Methylenetetrahydrofolate Reductase, Methionine Synthase, and Methionine Synthase Reductase Polymorphisms: A Randomized Controlled Trial.

Pokushalov Evgeny (2024) · Nutrients · n=54

Asciminib in Patients With CML-CP Previously Treated With ≥ 2 Tyrosine Kinase Inhibitors: 96-Week Results From the Japanese Subgroup Analysis of the ASCEMBL Study.

Minami Yosuke (2024) · International journal of hematology

Dolutegravir- Versus Efavirenz-Based Treatment in Pregnancy: Impact on Red Blood Cell Folate Concentrations in Pregnant Women and Their Infants.

Jacobson Denise L (2024) · The Journal of infectious diseases

Comparative study of choline alfoscerate as a combination therapy with donepezil: A mixed double-blind randomized controlled and open-label observation trial.

Lee Wankiun (2024) · Medicine · n=119

Nicotinamide riboside for peripheral artery disease: the NICE randomized clinical trial.

McDermott Mary M (2024) · Nature communications

Nanoliposomal irinotecan and fluorouracil plus leucovorin versus fluorouracil plus leucovorin in patients with cholangiocarcinoma and gallbladder carcinoma previously treated with gemcitabine-based therapies (AIO NALIRICC): a multicentre, open-label, randomised, phase 2 trial.

Vogel Arndt (2024) · The lancet. Gastroenterology & hepatology · n=49

Traditional Korean diet high in one-carbon nutrients increases global DNA methylation: implication for epigenetic diet.

Chun Sukyung (2024) · European journal of nutrition · n=52

Upfront Fluorouracil, Leucovorin, Oxaliplatin, and Irinotecan Plus Bevacizumab With or Without Atezolizumab for Patients With Metastatic Colorectal Cancer: Updated and Overall Survival Results of the ATEZOTRIBE Study.

Antoniotti Carlotta (2024) · Journal of clinical oncology : official journal of the American Society of Clinical Oncology · n=73

Bemarituzumab plus mFOLFOX6 as first-line treatment in East Asian patients with FGFR2b-overexpressing locally advanced or metastatic gastric/gastroesophageal junction cancer: subgroup of FIGHT final analysis.

Kang Yoon-Koo (2024) · Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · n=89

Brazil-TNT: A Randomized Phase 2 Trial of Neoadjuvant Chemoradiation Followed by FOLFIRINOX Versus Chemoradiation for Stage II/III Rectal Cancer.

Bugano Diogo Diniz Gomes (2024) · Clinical colorectal cancer · n=55

Nanoliposomal Irinotecan With Fluorouracil and Leucovorin or Gemcitabine Plus Cisplatin in Advanced Cholangiocarcinoma: A Phase II Study of the AIO Hepatobiliary-YMO Cancer Groups (NIFE-AIO-YMO HEP-0315).

Ettrich Thomas J (2024) · Journal of clinical oncology : official journal of the American Society of Clinical Oncology · n=49

A Randomized Control Trial of Dexketoprofen/Vitamin B (Thiamine, Pyridoxine and Cyanocobalamin) Fixed-Dose Combination in Post-Traumatic Grade I-II Cervical Sprains.

Delgado-García Pamela (2024) · Clinical drug investigation

Towards improved diagnosis: radiomics and quantitative biomarkers in 18 F-PSMA-1007 and 18 F-fluorocholine PET/CT for prostate cancer recurrence.

Panagiotidis Emmanouil (2024) · Nuclear medicine communications · n=106

Interpersonal Communication Strategies to Increase Iron-Folic Acid Supplement Consumption: Reduction in Anemia Through Normative Innovations (RANI) Project.

Ganjoo Rohini (2024) · Journal of health communication

Folic acid supplementation for stroke prevention: A systematic review and meta-analysis of 21 randomized clinical trials worldwide.

Zhang Nan (2024) · Clinical nutrition (Edinburgh, Scotland) · n=115559

Asciminib in Newly Diagnosed Chronic Myeloid Leukemia.

Hochhaus Andreas (2024) · The New England journal of medicine · n=201

Phentolamine and B vitamins for feeding intolerance in late preterm infants: a randomised trial.

Lv Yuan-Yuan (2024) · Asia Pacific journal of clinical nutrition · n=56

Efficacy of Danzhixiaoyao tablets combined with methylcobalamin tablets in the treatment of burning mouth syndrome: an open-label, randomized controlled trial.

Gao Ya (2024) · BMC oral health · n=78

Assessment of cardiac parameters after the administration of nicorandil before primary percutaneous coronary intervention.

Ilyas Maria (2024) · JPMA. The Journal of the Pakistan Medical Association · n=140

Maternal serum unmetabolized folic acid concentration following multivitamin and mineral supplementation with or without folic acid after 12 weeks gestation: A randomized controlled trial.

Sulistyoningrum Dian C (2024) · Maternal & child nutrition · n=103

Maternal folic acid supplementation to prevent preeclampsia: a systematic review and meta-analysis.

Cui Huaixing (2024) · Complementary therapies in medicine · n=222

The effect of niacin on inflammatory markers and adipokines: a systematic review and meta-analysis of interventional studies.

Rad Esmaeil Yousefi (2024) · European journal of nutrition

Olaparib with or without bevacizumab versus bevacizumab plus a fluoropyrimidine as maintenance therapy in advanced colorectal cancer: The randomized phase 3 LYNK-003 study.

Takashima Atsuo (2024) · European journal of cancer (Oxford, England : 1990) · n=309

Intranasal vitamin B12 administration in elderly patients: A randomized controlled comparison of two dosage regimens.

Tillemans Monique P H (2024) · British journal of clinical pharmacology

Influence of folic acid and vitamin B12 supplementation on arsenic methylation: A double-blinded, placebo-controlled trial in Bangladeshi children.

Martinez-Morata Irene (2024) · Environment international · n=240

Cetuximab plus FOLFOXIRI versus cetuximab plus FOLFOX as conversion regimen in RAS/BRAF wild-type patients with initially unresectable colorectal liver metastases (TRICE trial): A randomized controlled trial.

Wang De-Shen (2024) · PLoS medicine · n=72

Role of vitamin B12 and folic acid in treatment of Alzheimer's disease: a meta-analysis of randomized control trials.

Lee Chih-Ying (2024) · Aging

RENAL PROTECTIVE EFFECT AND CLINICAL ANALYSIS OF VITAMIN B 6 IN PATIENTS WITH SEPSIS.

Wang Yao (2024) · Shock (Augusta, Ga.) · n=128

Efficacy of 5% topical minoxidil versus 5 mg oral biotin versus topical minoxidil and oral biotin on hair growth in men: randomized, crossover, clinical trial.

Valentim Flávia de Oliveira (2024) · Anais brasileiros de dermatologia

Failure to Undergo Resection Following Neoadjuvant Therapy for Resectable Pancreatic Cancer: A Secondary Analysis of SWOG S1505.

Cloyd Jordan M (2024) · Journal of the National Comprehensive Cancer Network : JNCCN · n=11

Effect of probiotic administration during pregnancy on the functional diversity of the gut microbiota in healthy pregnant women.

Ma Guangyu (2024) · Microbiology spectrum

Changes in Nutritional Outcomes After Roux-en-Y Gastric Bypass: A Systematic Review and Meta-Analysis.

Duan Leizhen (2024) · Obesity surgery · n=5645

Folic acid supplementation on inflammation and homocysteine in type 2 diabetes mellitus: systematic review and meta-analysis of randomized controlled trials.

Mokgalaboni Kabelo (2024) · Nutrition & diabetes · n=426

Boosting the immunogenicity of the CoronaVac SARS-CoV-2 inactivated vaccine with Huoxiang Suling Shuanghua Decoction: a randomized, double-blind, placebo-controlled study.

Tang Ruying (2024) · Frontiers in immunology · n=70

Mitigation of retinol-induced skin irritation by physiologic lipids: Evidence from patch testing.

Fang Ye (2024) · Journal of cosmetic dermatology

Supramolecular salicylic acid combined with niacinamide in chloasma: a randomized controlled trial.

Xiong Ying (2024) · Clinical and experimental dermatology · n=15

Tazarotene is as effective and well-tolerated as imiquimod in the treatment of verruca plana: a comparative randomized controlled trial.

Nofal Hagar (2024) · Clinical and experimental dermatology · n=60

Predictors of post stroke cognitive impairment: VITATOPS cognition substudy.

Siow Isabel (2024) · Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · n=736

Nicotinamide in Combination with EGFR-TKIs for the Treatment of Stage IV Lung Adenocarcinoma with EGFR Mutations: A Randomized Double-Blind (Phase IIb) Trial.

Oh Hyung-Joo (2024) · Clinical cancer research : an official journal of the American Association for Cancer Research · n=55

Aseptic Skin Repair Dressing May Be a Vital Clinical Effect in Treatment of Facial Dermatitis.

Lu Wei (2025) · Alternative therapies in health and medicine · n=80

FOLFIRI Plus Durvalumab With or Without Tremelimumab in Second-Line Treatment of Advanced Gastric or Gastroesophageal Junction Adenocarcinoma: The PRODIGE 59-FFCD 1707-DURIGAST Randomized Clinical Trial.

Tougeron David (2024) · JAMA oncology · n=96

Resuscitation With Vitamin C, Hydrocortisone, and Thiamin in Children With Septic Shock: A Multicenter Randomized Pilot Study: Erratum.

Unknown (2024) · Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies

High-dose oral thiamine versus placebo for chronic fatigue in patients with primary biliary cholangitis: A crossover randomized clinical trial.

Bager Palle (2024) · PloS one · n=36

Efficacy comparison of combining cross-linking and refractive laser ablation in progressive keratoconus: systematic review and meta-analysis.

Achiron Asaf (2024) · Canadian journal of ophthalmology. Journal canadien d'ophtalmologie

Outcomes of Hepatic Artery-Based Therapies and Systemic Multiagent Chemotherapy in Unresectable Colorectal Liver Metastases: A Systematic Review and Meta-analysis.

Sugumar Kavin (2024) · Annals of surgical oncology

Hematological parameters in patients with recurrent Aphthous Stomatitis: a systematic review and meta-analysis.

Mousavi Tahoora (2024) · BMC oral health

Radiation Therapy Quality Assurance Analysis of Alliance A021501: Preoperative mFOLFIRINOX or mFOLFIRINOX Plus Hypofractionated Radiation Therapy for Borderline Resectable Adenocarcinoma of the Pancreas.

Tchelebi Leila T (2024) · International journal of radiation oncology, biology, physics · n=39

The Effect of Niacinamide Supplementation on Phosphate Concentrations in Dutch Dialysis Patients: A Randomized Crossover Trial.

Schepers Lara (2024) · Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation

Persistent COVID-19 parosmia and olfactory loss post olfactory training: randomized clinical trial comparing central and peripheral-acting therapeutics.

Cantone Elena (2024) · European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · n=85

Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study.

Qiu Yu (2024) · Clinical nutrition (Edinburgh, Scotland)

Malnutrition and vitamin deficiencies after surgery for esophageal and gastric cancer: A metanalysis.

Finze Alida (2024) · Clinical nutrition ESPEN

Optimal folic acid dosage in lowering homocysteine: Precision Folic Acid Trial to lower homocysteine (PFAT-Hcy).

Huang Xiao (2024) · European journal of nutrition · n=2163

Clinical Efficacy of Sodium Cantharidate Vitamin B6 Combined with Concurrent Chemoradiotherapy in the Treatment of Local Advanced Cervical Cancer and its Influence on Tumor Markers.

Lu Dongfang (2024) · Alternative therapies in health and medicine · n=120

Effects of folic acid supplementation on cognitive impairment: A meta-analysis of randomized controlled trials.

Xu Manru (2024) · Journal of evidence-based medicine · n=3604

Randomized clinical trial comparing customized corneal crosslinking: epi-on in high oxygen and epi-off in room air for keratoconus.

Elving Sofie (2024) · Journal of cataract and refractive surgery · n=32

Adjuvant Gemcitabine Versus Neoadjuvant/Adjuvant FOLFIRINOX in Resectable Pancreatic Cancer: The Randomized Multicenter Phase II NEPAFOX Trial.

Goetze Thorsten O (2024) · Annals of surgical oncology · n=126

Drug Efficacy in the Treatment of Antipsychotic-Induced Akathisia: A Systematic Review and Network Meta-Analysis.

Gerolymos Cyril (2024) · JAMA network open · n=10

A Phase II Study of FOLFIRI Plus Ziv-Aflibercept After Trifluridine/Tipiracil Plus Bevacizumab in Patients with Metastatic Colorectal Cancer: WJOG 11018G.

Matsumoto Toshihiko (2024) · Targeted oncology · n=26

Does an antihypertensive diet cost more? Analysis from the Chinese Heart-Healthy diet trial.

Guo Yishan (2024) · Public health nutrition

Preconception Micronutrient Supplementation Affects Maternal BMI and Body Composition Postpartum: A Randomized Controlled Trial in Vietnam.

Ramakrishnan Usha (2024) · The Journal of nutrition · n=1599

Dosage exploration of combined B-vitamin supplementation in stroke prevention: a meta-analysis and systematic review.

Zhang Nan (2024) · The American journal of clinical nutrition · n=76664

Efficacy of nicorandil and ranolazine in prevention of contrast-induced nephropathy in patients with mild-to-moderate renal dysfunction: a randomized controlled trial.

Yusuf Jamal (2024) · Coronary artery disease · n=315

The effects of prenatal and postnatal high-dose vitamin B-12 supplementation on human milk vitamin B-12: a randomized, double-blind, placebo-controlled trial in Tanzania.

Wang Dongqing (2024) · The American journal of clinical nutrition · n=412

Efficacy and Safety of Nicorandil in the Treatment of Stable Angina Pectoris.

Wang Xuan (2024) · Alternative therapies in health and medicine · n=30

Thiamine as a metabolic resuscitator after in-hospital cardiac arrest.

Berg Katherine M (2024) · Resuscitation · n=36

Thiamine as a metabolic resuscitator after out-of-hospital cardiac arrest.

Donnino Michael W (2024) · Resuscitation · n=93

Randomized phase II study of FOLFIRI plus ramucirumab versus FOLFOXIRI plus ramucirumab as first-line treatment for metastatic colorectal cancer: WJOG9216G (RECAST).

Kito Yosuke (2026) · European journal of cancer (Oxford, England : 1990) · n=122