Ashwagandha (KSM-66)

An investigation into the stress-relieving and pharmacological actions of an ashwagandha extract

Salve J, et al. (2019) · Medicine · n=58

A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of ashwagandha root extract in reducing stress and anxiety

Chandrasekhar K, et al. (2012) · Indian J Psychol Med · n=64

Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study

Langade D, et al. (2019) · Cureus · n=60

Effects of Root Extract of Ashwagandha (Withania somnifera) on Perception of Recovery and Muscle Strength in Female Athletes.

Coope OC (2025) · European journal of sport science

Effect of ashwagandha (Withania somnifera) extract with Sominone (Somin-On™) to improve memory in adults with mild cognitive impairment: A randomized, double-blind, placebo-controlled study.

Rai HP (2025) · Journal of psychopharmacology (Oxford, England)

Superior Bioavailability of a Novel 1.5% Ashwagandha Formulation (Zenroot™): A Randomized, Double-Blind, Single-Dose, Comparative, Oral Bioavailability Study in Healthy Adults.

Ramapalaniappan A (2025) · Advances in therapy

Ashwagandha Does Not Enhance the Effect of High-Intensity Interval Training on Selected Energy Metabolism Parameters in Young Healthy Men.

Charmas M (2025) · Nutrients

Effects of ashwagandha (Withania somnifera) on mental health in adults: A systematic review and dose-response meta-analysis of randomized controlled trials.

Alsanie SA (2026) · Complementary therapies in medicine

A proprietary herbal extract of ashwagandha root for stress and anxiety in healthy adults: a randomized, double-blind, three-arm, placebo-controlled efficacy and safety study.

West RE (2026) · Journal of medicine and life

A New Ashwagandha Formulation (Zenroot™) Alleviates Stress and Anxiety Symptoms While Improving Mood and Sleep Quality: A Randomized, Double-Blind, Placebo-Controlled Clinical Study.

Mahadevan M (2025) · Advances in therapy

Effects of multi-herb and ashwagandha root formulas on stress modulation: a randomized, double-blind, placebo-controlled clinical study.

McKinney E (2026) · Trials

Dual impact of Ashwagandha: Significant cortisol reduction but no effects on perceived stress - A systematic review and meta-analysis.

Albalawi AA (2025) · Nutrition and health · n=488

Efficacy and safety of Ashwagandha root extract sustained-release (AshwaSR) capsules in healthy adult, stressed subjects: A randomized, double-blind, placebo-controlled, parallel-group, 3-arm clinical trial.

Thanawala S (2026) · Medicine

Efficacy and safety of Ashwagandha (Withania somnifera) root extract on stress and weight management in adults: a prospective, randomized, double-blind, placebo-controlled study.

Pakhale K (2025) · Journal of medicine and life · n=100

Ashwagandha Root Extract Stabilises Physiological Stress Responses in Male and Female Team Sports Athletes During Pre-Season Training.

Coope OC (2026) · Nutrients