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Omega-3 (EPA/DHA)

Also known as: fish oil, EPA, DHA, omega 3 fatty acids

AAdequate Evidence71/100183 studies referenced

Common dosage

2-3g combined EPA/DHA daily

Category

fatty acid

Description

Essential fatty acids with strong evidence for cardiovascular health, inflammation reduction, and cognitive function. EPA is more anti-inflammatory; DHA supports brain structure.

Safety & interactions

Choose triglyceride form over ethyl ester. May thin blood — consult doctor if on blood thinners.
Check all interactions →

What the research shows

Reduces inflammation and muscle damage in athletes, particularly recreational athletes, leading to faster recovery

Improves exercise performance and fat burning during endurance activities

moderate evidence2 studies:Nutrients (2026)Nutrients (2026)

May help lower cholesterol levels, though the strength of evidence is unclear

emerging evidence1 study:Nutrients (2026)

Does not significantly improve muscle mass or strength when combined with resistance training and high protein intake

moderate evidence1 study:Nutrients (2026)

May help improve sarcopenia and muscle health in older adults when combined with exercise and protein

Shows no significant effects on pregnancy outcomes in low-risk pregnant women

moderate evidence1 study:Journal of tropical pediatrics (2026)

Is safe with no serious adverse effects reported at recommended doses

Researched health areas

Health domains where Omega-3 (EPA/DHA) has published research. Click any domain to see all supplements and habits for that area.

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Questions about Omega-3 (EPA/DHA)

Studies on Omega-3 (EPA/DHA) (183)

ProtocolEngine provides general health information based on published research. This is not medical advice. Consult a healthcare professional before starting any supplement or health protocol.