ProtocolEngine.io

Magnesium Glycinate

Also known as: magnesium bisglycinate, chelated magnesium, mag glycinate

SStrong Evidence83/10034 studies referenced

Common dosage

200-400mg daily

Category

mineral

Description

Highly bioavailable form of magnesium that supports sleep quality, anxiety reduction, muscle relaxation, and cardiovascular health. The glycinate form is preferred for its superior absorption and minimal GI side effects.

Safety & interactions

Generally safe. May cause loose stools at high doses. Split doses >300mg for better absorption.
Check all interactions →

What the research shows

May help improve blood sugar control and reduce fasting blood glucose levels in people with type 2 diabetes

May help improve cholesterol and blood pressure levels in people with type 2 diabetes

May help reduce fatigue and improve sleep quality in people with fibromyalgia

emerging evidence1 study:Journal of dietary supplements (2025)

May help improve mood and depressive symptoms when used alongside antidepressant medication

May help reduce complications after thyroid surgery, including improving quality of life and preventing low calcium levels

Generally well-tolerated with mild side effects comparable to placebo

Researched health areas

Health domains where Magnesium Glycinate has published research. Click any domain to see all supplements and habits for that area.

Get notified when new research drops

  • Alerts when new studies affect this supplement
  • Add to your personal stack and track interactions
  • Weekly digest with evidence score changes

Premium

Upgrade to access full study-level evidence breakdowns for each outcome.

View pricing

Questions about Magnesium Glycinate

Studies on Magnesium Glycinate (34)

ProtocolEngine provides general health information based on published research. This is not medical advice. Consult a healthcare professional before starting any supplement or health protocol.